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KLK11 mRNA expression could be considered as a new molecular prognostic biomarker in colorectal adenocarcinoma
hK11 expression in gastric cancer appears to be associated with a better prognosis. hK11 may be a prognostic biomarker of gastric cancer.
The aim of this study was to monitor serum levels of two microRNAs (miR-21 and miR-141) and three kallikreins (hK3/PSA, hK11, and hK13) before and 1, 5, and 30 days after radical prostatectomy.
Our data showed that UVB-induced TSLP (show TSLP ELISA Kits) might increase secretion of the T-helper type 2-attracting chemokine (c-c motif) ligand 17 (show CCL17 ELISA Kits) by human dendritic cells.
HOXB8 (show HOXB8 ELISA Kits) and KLK11 may be classified as valuable biomarkers, as they can predict the effects of FOLFOX4 chemotherapy in primary advanced colorectal cancer patients
Human airway trypsin-like protease (show TMPRSS11D ELISA Kits) can stimulate mucin5AC hypersecretion through a PAR2 (show F2RL1 ELISA Kits)-mediated signaling pathway in 16HBE cells.
Patients harboring KLK11-positive tumors had a significantly decreased risk of death.
Low KLK11 protein expression is associated with gastric cancer.
For the first time, we report lower expression of KLK11 in CaP compared to BPH (show GLI3 ELISA Kits) and slight upregulation of KLK11 in advanced tumors compared to localized ones
the up-regulation of TMPRSS2 (show TMPRSS2 ELISA Kits) and the down-regulation of KLK11 in advanced and more aggressive tumors may open the feasibility of being used as biomarkers distinguishing the tumor aggressiveness as well as novel prognostic indicators for prostate cancer.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
kallikrein-related peptidase 11
, kallikrein 11
, protease, serine, 20
, serine protease 20
, trypsin-like protease