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|Application / Reactivity||Human||Dog (Canine)||Rat (Rattus)|
|Western Blotting (WB)||53 Antibodies||2 Antibodies||9 Antibodies|
|Immunoprecipitation (IP)||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies||5 Antibodies|
|Immunohistochemistry (IHC)||10 Antibodies||2 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies||11 Antibodies|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|ELISA||27 Antibodies||1 Antibodies||2 Antibodies|
|Antigen||Kallikrein 5 (KLK5) Antibodies|
|Epitope||Internal Region Alternatives|
|Reactivity||Dog (Canine), Human, Rat (Rattus) Alternatives|
|Conjugate||This Kallikrein 5 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-Kallikrein 5 AntibodyTarget Details Kallikrein 5 Application Details Handling References for anti-Kallikrein 5 Antibody (ABIN374828) Images
|Specificity||This antibody recognizes KLK5.|
Species reactivity (expected):Rat and Canine.
Species reactivity (tested):Human.
|Immunogen||Peptide with sequence KAGRDSCQGD, from the internal region of the protein sequence|
Target Details Kallikrein 5Product Details anti-Kallikrein 5 Antibody Application Details Handling References for anti-Kallikrein 5 Antibody (ABIN374828) Images back to top
|Alternative Name||KLK5 / Kallikrein-5 (KLK5 Antibody Abstract)|
|Background||Kallikrein 5 was originally described from the skin as an enzyme involved in turnover of the stratum corneum, and later cloned from human EST libraries as a Kallikrein like enzyme. The skin is known to contain trypsin like and chymotrypsin like proteinases of 32 kDa and 25 kDa respectively, and these were determined to be hK5 and hK7. Kallikrein 5 is found is greatest abundance in the skin, and also in the brain, with lesser signal in the kidney, lung, mammary gland, and testis. Human breast milk is reported to contain high levels of Kallikrein 5. Less stringent PCR detects hK5 in many tissues, and analysis of cell lines by Western blot shows that many cell lines make hK5.Synonyms: KLK-5, KLK-L2, Kallikrein-Like Protein 2, SCTE, Stratum corneum tryptic enzyme|
Application DetailsProduct Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Handling References for anti-Kallikrein 5 Antibody (ABIN374828) Images back to top
Peptide ELISA: 1/4000. Western Blot: 0.1-0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Application Details References for anti-Kallikrein 5 Antibody (ABIN374828) Images back to top
|Buffer||Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-Kallikrein 5 Antibody (ABIN374828)Product Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Application Details Handling Images back to top
Michael, Pampalakis, Mikolajczyk, Malm, Sotiropoulou, Diamandis: "Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression." in: The Journal of biological chemistry, Vol. 281, Issue 18, pp. 12743-50, 2006
ImagesProduct Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Application Details Handling References for anti-Kallikrein 5 Antibody (ABIN374828) back to top