Kallikrein 5 antibody (C-Term)

Catalog No. ABIN7268064

Product Details anti-Kallikrein 5 Antibody

Target: Kallikrein 5 (KLK5)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: KLK5 Rabbit pAb

Sequence: FPKVLQCLNI SVLSQKRCED AYPRQIDDTM FCAGDKAGRD SCQGDSGGPV VCNGSLQGLV SWGDYPCARP NRPGVYTNLC KFTKWIQETI QANS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human KLK5 (NP_001070959.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Kallikrein 5

Target: Kallikrein 5 (KLK5)

Alternative Name: KLK5 (KLK5 Products)

Synonyms: KLK-L2 antibody, KLKL2 antibody, SCTE antibody, 1110030O19Rik antibody, KAL antibody, KALA antibody, Klk1 antibody, Klk5 antibody, RATKALA antibody, kallikrein related peptidase 5 antibody, kallikrein related-peptidase 5 antibody, kallikrein 5-like antibody, KLK5 antibody, Klk5 antibody, Klk5l antibody

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.,KLK5,KLK-L2,KLKL2,SCTE,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,KLK5

Molecular Weight: 32kDa

Gene ID: 25818

UniProt: Q9Y337

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling