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anti-Human MBL2 antibody for Neutralization

Recommended MBL2 Antibody (supplied by: Log in to see )

Antigen
Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) Antibodies
  • Ab2-001
  • Ab2-011
  • cMBl
  • COLEC1
  • collectin
  • HSMBPC
  • L-MBP
  • MBL
  • MBL-C
  • MBL1
  • mbl2
  • MBL2D
  • MBP
  • MBP-C
  • MBP1
  • MBPD
  • pMBP-27
Reactivity
Human
92
18
12
4
2
2
1
1
1
Host
Mouse
67
34
8
3
Clonality
Monoclonal
Conjugate
This MBL2 antibody is un-conjugated
8
6
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Neutralization (Neut), Western Blotting (WB)
90
73
31
13
11
11
10
3
1
1
1
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Catalog No. ABIN1108118
$ 940.50
Plus shipping costs $45.00

Top referenced anti-MBL2 antibody for Neutralization

Similar anti-MBL2 Antibodies

Application / Reactivity Human
ELISA 61 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 26 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 78 Antibodies

General

Antigen Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) Antibodies
Reactivity Human
(92), (18), (12), (4), (2), (2), (1), (1), (1)
Host Mouse
(67), (34), (8), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MBL2 antibody is un-conjugated
(8), (6), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Neutralization (Neut), Western Blotting (WB)
(90), (73), (31), (13), (11), (11), (10), (3), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-MBL2 Antibody

Target Details MBL2 Application Details Handling References for anti-MBL2 Antibody (ABIN1108118) Images
Cross-Reactivity (Details) Species reactivity (tested):Human.
Clone 3-00E-007
Isotype IgG1

Target Details MBL2

Product Details anti-MBL2 Antibody Application Details Handling References for anti-MBL2 Antibody (ABIN1108118) Images back to top
Antigen
Alternative Name Mannan Binding Protein (MBL2 Antibody Abstract)
Background Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of Collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species.Synonyms: MBL, MBL2, MBP, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin, Mannose-binding protein C
Gene ID 9606
UniProt P11226
Research Area Complement Factors, Receptors, Serum/Plasma Proteins, Inflammation
Pathways Complement System

Application Details

Product Details anti-MBL2 Antibody Target Details MBL2 Handling References for anti-MBL2 Antibody (ABIN1108118) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MBL2 Antibody Target Details MBL2 Application Details References for anti-MBL2 Antibody (ABIN1108118) Images back to top
Concentration 0,1 mg/mL
Buffer PBS, 0,02 % sodium azide, 0,1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-MBL2 Antibody (ABIN1108118)

Product Details anti-MBL2 Antibody Target Details MBL2 Application Details Handling Images back to top
Background publications

de Vries, Walter, Peutz-Kootstra, Wolfs, van Heurn, Buurman: "The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury." in: The American journal of pathology, Vol. 165, Issue 5, pp. 1677-88, 2004

Nauta, Castellano, Xu, Woltman, Borrias, Daha, van Kooten, Roos: "Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 5, pp. 3044-50, 2004

Nauta, Raaschou-Jensen, Roos, Daha, Madsen, Borrias-Essers, Ryder, Koch, Garred: "Mannose-binding lectin engagement with late apoptotic and necrotic cells." in: European journal of immunology, Vol. 33, Issue 10, pp. 2853-63, 2003

Hisano, Matsushita, Fujita, Endo, Takebayashi: "Mesangial IgA2 deposits and lectin pathway-mediated complement activation in IgA glomerulonephritis." in: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 38, Issue 5, pp. 1082-8, 2001

Muto, Takada, Matsumoto: "Biological activities of human mannose-binding lectin bound to two different ligand sugar structures, Lewis A and Lewis B antigens and high-mannose type oligosaccharides." in: Biochimica et biophysica acta, Vol. 1527, Issue 1-2, pp. 39-46, 2001

Matsushita, Takahashi, Hatsuse, Kawakami, Fujita: "Human mannose-binding protein is identical to a component of Ra-reactive factor." in: Biochemical and biophysical research communications, Vol. 183, Issue 2, pp. 645-51, 1992

Furano, Bradley, Childers: "The conformation of the ribonucleic acid in ribosomes. Dye stacking studies." in: Biochemistry, Vol. 5, Issue 9, pp. 3044-56, 1970