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Minichromosome Maintenance Deficient 4 Proteins

(Minichromosome Maintenance Deficient 4 (MCM4))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
MCM4 Protein (AA 1-863) (GST tag) MCM4 Protein (AA 1-863) (GST tag) MCM4 Protein (AA 1-863) (GST tag) (ABIN1310553)

MCM4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

MCM4 Protein (AA 267-366) (GST tag) MCM4 Protein (AA 267-366) (GST tag) MCM4 Protein (AA 267-366) (GST tag) (ABIN1310555)

MCM4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

MCM4 Protein (AA 2-863) (His tag) MCM4 Protein (AA 2-863) (His tag) MCM4 Protein (AA 2-863) (His tag) (ABIN3093724)

Crystallography grade MCM4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

Minichromosome Maintenance Deficient 4 Proteins by Grade

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Minichromosome Maintenance Deficient 4 Proteins by Origin

Find Minichromosome Maintenance Deficient 4 Proteins for a variety of species such as anti-Human Minichromosome Maintenance Deficient 4, anti-Mouse Minichromosome Maintenance Deficient 4. The species listed below are among those available. Click on a link to go to the corresponding products.

Minichromosome Maintenance Deficient 4 Proteins by Source

Here you will find Minichromosome Maintenance Deficient 4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Minichromosome Maintenance Deficient 4 Proteins by Protein Type

Here you can find Minichromosome Maintenance Deficient 4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Minichromosome Maintenance Deficient 4 Proteins by Application

Find Minichromosome Maintenance Deficient 4 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Minichromosome Maintenance Deficient 4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1310553
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310555
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093724
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134265
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2725632
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2725633
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Minichromosome Maintenance Deficient 4 Proteins

Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).

Aliases for Minichromosome Maintenance Deficient 4 Proteins

minichromosome maintenance complex component 4 L homeolog (mcm4.L) Proteins
minichromosome maintenance complex component 4 S homeolog (mcm4.S) Proteins
minichromosome maintenance complex component 4 (MCM4) Proteins
minichromosome maintenance complex component 4 (mcm4) Proteins
minichromosome maintenance complex component 4 (Mcm4) Proteins
19G Proteins
AI325074 Proteins
AU045576 Proteins
cb1025 Proteins
cdc21 Proteins
CDC21 Proteins
Cdc21 Proteins
CDC54 Proteins
fc12c09 Proteins
fj85g09 Proteins
hCdc21 Proteins
hm:zeh1616 Proteins
mcdc21 Proteins
Mcmd4 Proteins
mKIAA4003 Proteins
NKCD Proteins
NKGCD Proteins
P1-CDC21 Proteins
wu:fc12c09 Proteins
wu:fj85g09 Proteins
zeh1616 Proteins
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