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Browse our ADRA2A Proteins (ADRA2A)

Full name:
Adrenergic, alpha-2A-, Receptor Proteins (ADRA2A)
On are 5 Adrenergic, alpha-2A-, Receptor (ADRA2A) Proteins from 2 different suppliers available. Additionally we are shipping ADRA2A Antibodies (78) and ADRA2A Kits (15) and many more products for this protein. A total of 103 ADRA2A products are currently listed.
Adra-2, Adra-2a, ADRA2, ADRA2A, ADRA2R, ADRAR, alpha(2A)AR, alpha2-C10, alpha2A, alpha2A-AR, ALPHA2AAR, AW122659, CA2-47, PORA2AR, RATRG20, RG20, ZNF32
list all proteins Gene Name GeneID UniProt
ADRA2A 11551  
ADRA2A 150 P08913
Rat ADRA2A ADRA2A 25083 P22909

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ADRA2A Proteins (ADRA2A) by Origin

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More Proteins for ADRA2A Interaction Partners

Mouse (Murine) Adrenergic, alpha-2A-, Receptor (ADRA2A) interaction partners

  1. This study showed that reduced expression of the alpha2A-adrenoceptor (Adra2a) which modulate antidepressant action in hippocampus.

  2. Fzd5 and Trvp6 are expressed in the epithelial layer of the prospective pyroric and glandular stomach, respectively and Adra2a is expressed in the mesenchymal region of the stomach primordium at the beginning of morphogenesis.

  3. The sympathetic hyperactivity present in alpha2A/alpha2C-ARKO (show CYP19A1 Proteins) mice alters vascular reactivity only in certain types of arteries

  4. Data indicate that activation of alpha(2A) adrenergic receptor (alpha(2A)AR) signaling disrupts transgenic amyloid precursor protein (APP (show APP Proteins)) interaction with sorting-related receptor with A repeat (SorLA (show SORL1 Proteins)) in cells and brain.

  5. Thus, our study reveals distinct actions of PBN afferents within the BNST and suggests that alpha(2A)-AR agonists may filter excitatory transmission in the BNST by inhibiting a component of the PBN input while enhancing the actions of other inputs.

  6. The time course of Adra2a- and dopamine D2R (show DRD2 Proteins)-mediated transmission reflects underlying differences in the extent of spillover and pooling of inhibitory postsynaptic potentials (IPSPs).

  7. Activation of alpha2A-AR and muscarinic M3 receptors affects the initial [Ca(2 (show CA2 Proteins)+)] response to increase of glucose from 3 to 20mM in BETA-cells.

  8. Canonical betaAR-mediated signaling coupled to PKA activation results in phosphorylation of spinophilin (show PPP1R9B Proteins), disrupting its interaction with alpha2AARs and accelerating alpha2AAR endocytic responses.

  9. conformational change of alpha(2A)AR by voltage is independent from receptor-G protein docking and regulates receptor signaling, including beta-arrestin binding, activation of G proteins, and G protein-activated inwardly rectifying K(+) currents

  10. adra2 receptor stimulation significantly modifies migration of cortical interneurons.

Human Adrenergic, alpha-2A-, Receptor (ADRA2A) interaction partners

  1. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (show ADCY5 Proteins), ADRA2A, CDKAL1 (show CDKAL1 Proteins), CDKN2A/B, GRB10 (show GRB10 Proteins), and TCF7L2 (show TCF7L2 Proteins)

  2. The ADRA2A C-1291G and COMT (show COMT Proteins) Val158Met genotypes and sex interact in predicting detection and perception of emotional valence in facial expressions

  3. ADRA2a is associated with heart rate recovery after exercise.

  4. Study is in line with previous reports of an association between ADRA2A gene variants and general reaction time variability during response selection tasks

  5. Genetic association of ADRA2A single nucleotide polymorphism with metabolic syndrome and high level insulin (show INS Proteins) among the Tatars

  6. The rs10885122G>T polymorphism of the ADRA2A gene was not associated with type 2 diabetes mellitus in Euro-Brazilians, and carriers of the T allele had lower body weight in the presence of type 2 diabetes mellitus.

  7. Common polymorphisms in the ADRA2A gene are not associated with orthostatic hypotension risk in Chinese.

  8. The alpha2a AR expression in breast cancer was associated with Her-2 (show ERBB2 Proteins) status (P = 0.048) and a marginal significance was observed between alpha2a AR expression and estrogen receptor (show ESR1 Proteins) (P = 0.061).

  9. Study found evidence that DNA variation in the ADRA2A gene may be causally related to ADHD-like behaviors, in part through its influence on intra-individual variability

  10. The accuracy of prediction for breast cancer relapse based solely on the expression of ADRA2A gene is high.

Pig (Porcine) Adrenergic, alpha-2A-, Receptor (ADRA2A) interaction partners

  1. islets express mRNA transcripts for sulfonylurea receptor 1 (Sur1 (show ABCC8 Proteins)), inward rectifying potassium channel (show KCNAB2 Proteins) (Kir6.2 (show KCNJ11 Proteins), associated with Sur1 (show ABCC8 Proteins)), glucagon-like peptide 1 receptor (GLP1R (show GLP1R Proteins)), and adrenergic receptor alpha 2A (ADRalpha2A)

Rabbit Adrenergic, alpha-2A-, Receptor (ADRA2A) interaction partners

  1. Proliferation of Achilles tenocytes in overuse tendinosis is induced by ADRA2A stimulation and inhibited by an ADRA2A blocker.

ADRA2A Protein Profile

Protein Summary

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons\; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Alternative names and synonyms associated with ADRA2A

  • adrenergic, alpha-2A-, receptor (adra2a)
  • adrenergic, alpha-2A-, receptor (ADRA2A)
  • adrenoceptor alpha 2A (ADRA2A)
  • adrenoceptor alpha 2A (adra2a)
  • alpha-2A adrenergic receptor-like (LOC100414445)
  • adrenergic receptor, alpha 2a (Adra2a)
  • adrenoceptor alpha 2A (Adra2a)
  • Adra-2 protein
  • Adra-2a protein
  • ADRA2 protein
  • ADRA2A protein
  • ADRA2R protein
  • ADRAR protein
  • alpha(2A)AR protein
  • alpha2-C10 protein
  • alpha2A protein
  • alpha2A-AR protein
  • ALPHA2AAR protein
  • AW122659 protein
  • CA2-47 protein
  • PORA2AR protein
  • RATRG20 protein
  • RG20 protein
  • ZNF32 protein

Protein level used designations for ADRA2A

alpha(2A)AR , alpha-2A adrenergic receptor , alpha-2A adrenoceptor , alpha-2A adrenoreceptor , alpha-2AAR , alpha2A-adrenergic receptor , adrenergic receptor subtype alpha-2A , adrenergic, alpha-2A-, receptor , alpha-2A-adrenergic receptor , adrenergic receptor alpha-2A , alpha-2A adrenergic receptor-like , subtype alpha2-C10 , adrenergic alpha 2A, receptor , adrenergic, alpha-2, receptor , alpha-2-adrenergic receptor , alpha-2D adrenergic receptor , alpha-2 adrenergic receptor subtype C10 , alpha-2-adrenergic receptor, platelet type , alpha-2AAR subtype C10 , adrenergic receptor, alpha 2a , alpha 2A adrenoceptor

266750 Danio rerio
428980 Gallus gallus
466201 Pan troglodytes
664736 Felis catus
695684 Macaca mulatta
780304 Xenopus (Silurana) tropicalis
100170317 Ovis aries
100414445 Callithrix jacchus
100459426 Pongo abelii
11551 Mus musculus
100135475 Cavia porcellus
282135 Bos taurus
150 Homo sapiens
25083 Rattus norvegicus
486888 Canis lupus familiaris
399501 Sus scrofa
100009424 Oryctolagus cuniculus
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