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Browse our Trefoil Factor 1 Proteins (TFF1)

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Trefoil Factor 1 Proteins (TFF1)
On www.antibodies-online.com are 37 Trefoil Factor 1 (TFF1) Proteins from 14 different suppliers available. Additionally we are shipping Trefoil Factor 1 Antibodies (214) and Trefoil Factor 1 Kits (42) and many more products for this protein. A total of 297 Trefoil Factor 1 products are currently listed.
Synonyms:
Bcei, D21S21, HP1.A, HPS2, p1, p1-a, pNR-2, Ps2, tff1, xP1, xp1-L
list all proteins Gene Name GeneID UniProt
TFF1 81751 O88777
TFF1 7031 P04155
TFF1 21784 Q08423

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Trefoil Factor 1 Proteins (TFF1) by Origin

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Top referenced Trefoil Factor 1 Proteins

  1. Human TFF1 Protein expressed in Escherichia coli (E. coli) - ABIN667932 : Gött, Beck, Machado, Carneiro, Schmitt, Blin: Human trefoil peptides: genomic structure in 21q22.3 and coordinated expression. in European journal of human genetics : EJHG 1997 (PubMed)
    Show all 2 references for ABIN667932

  2. Human TFF1 Protein expressed in Wheat germ - ABIN1322569 : Kubota, Yamauchi, Sugano, Kawasaki, Sugiyama, Matsuzawa, Akamatsu, Ohmoto, Ota et al.: Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous ... in Digestive diseases and sciences 2011 (PubMed)
    Show all 2 references for ABIN1322569

More Proteins for Trefoil Factor 1 Interaction Partners

Xenopus laevis Trefoil Factor 1 (TFF1) interaction partners

  1. expression of xP1-L was detected in stage 41/42 tadpoles; in situ hybridization showed that xP1-L was localized to surface mucous cells of the larval stomach

Human Trefoil Factor 1 (TFF1) interaction partners

  1. we found TFF1 plays an oncogenic role in mucinous ovarian cancer

  2. These results show increased levels of TFF1 and TFF3 (show TFF3 Proteins) in Chronic Kidney Disease patients with a pronounced elevation of urinary TFF1 in lower Chronic Kidney Disease stages.

  3. Loss of TFF1 could be a critical step in promoting the H. pylori-mediated oncogenic activation of beta-catenin (show CTNNB1 Proteins) and gastric tumorigenesis.

  4. We have established a novel, three-protein biomarker panel that is able to detect patients with early-stage pancreatic cancer in urine specimens:LYVE-1, REG1A (show REG1A Proteins), and TFF1 were selected as candidate biomarkers

  5. These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 have protective effects for GC and contribute to the development of GC in Korean individuals.

  6. Findings underscore an important protective role of TFF1 in abrogating H. pylori-mediated inflammation, a crucial hallmark of gastric tumorigenesis. Loss of TFF1 expression could be an important step in H. pylori-mediated gastric carcinogenesis.

  7. trefoil factor 1 demonstrated breast specificity but was inferior to mammaglobin and GATA protein binding 3

  8. Data indicate that microRNA miR218-5p negatively regulates trefoil factor 1 (TFF1) in an extracellular signal-regulated kinases Erk1/2-dependent manner.

  9. Trefoil Factor 1 levels can influence copper excretion and copper related toxicity.

  10. data clearly show that the expression of TFF3 (show TFF3 Proteins) in retinoblastoma cell lines is epigenetically regulated, whereas the level of TFF1 and TFF2 (show TFF2 Proteins) seems to be regulated by other or additional mechanisms

Mouse (Murine) Trefoil Factor 1 (TFF1) interaction partners

  1. Loss of TFF1 could be a critical step in promoting the H. pylori-mediated oncogenic activation of beta-catenin (show CTNNB1 Proteins) and gastric tumorigenesis.

  2. Findings underscore an important protective role of TFF1 in abrogating H. pylori-mediated inflammation, a crucial hallmark of gastric tumorigenesis. Loss of TFF1 expression could be an important step in H. pylori-mediated gastric carcinogenesis.

  3. TFF1 and TFF3 (show TFF3 Proteins) peptides might be involved in the complex processes of nervous system development and differentiation and brain plasticity.

  4. Loss of TFF1 promotes beta-catenin activation and gastric tumorigenesis through regulation of PP2A, a major regulator AKT-GSK3Beta signaling.

  5. Loss of Tff1 and high expression of cox2 are associated with gastric adenomas.

  6. increased oncogenic potential of MCF7 cells in the absence of TFF1 was confirmed in vivo in nude mice

  7. loss of TFF1 leads to activation of IKK (show CHUK Proteins) complex-regulated NF-kappaB (show NFKB1 Proteins) transcription factors and is an important event in shaping the NF-kappaB (show NFKB1 Proteins)-mediated inflammatory response during the progression to gastric tumorigenesis

  8. Initiation of antral gastric cancer is associated with progressive epigenetic silencing of TFF1, which can be suppressed by the hormone gastrin (show GAST Proteins).

  9. Studies indicate that TFF1-knockout mice demonstrate amplification and invasiveness of gastric stem/progenitor cells.

  10. gene activation mediated by SHP2 (show PTPN11 Proteins) and STAT (show STAT1 Proteins) pathways in gp130 (show LRPPRC Proteins) mutant mice

Pig (Porcine) Trefoil Factor 1 (TFF1) interaction partners

  1. Colon from infected swine had increased expression of MUC5AC and TFF1 relative to controls.

  2. Weaning was not associated with fifferential TFF1 expression in the distal jejunum and ileum.

Trefoil Factor 1 (TFF1) Protein Profile

Protein Summary

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Alternative names and synonyms associated with Trefoil Factor 1 (TFF1)

  • trefoil factor 1 (tff1-b)
  • trefoil factor 1 (TFF1)
  • presenilin 2 (Psen2)
  • trefoil factor 1 (Tff1)
  • trefoil factor 1 (tff1-a)
  • trefoil factor 1-like (LOC100358238)
  • Bcei protein
  • D21S21 protein
  • HP1.A protein
  • HPS2 protein
  • p1 protein
  • p1-a protein
  • pNR-2 protein
  • Ps2 protein
  • tff1 protein
  • xP1 protein
  • xp1-L protein

Protein level used designations for Trefoil Factor 1 Proteins (TFF1)

trefoil factor 1 , P-domain peptide , trefoil factor family peptide 1 , PS-2 , presenilin-2 , breast cancer estrogen-inducible protein , breast cancer estrogen-inducible sequence , gastrointestinal trefoil protein pS2 , polypeptide P1.A , protein pS2 , trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in) , P-domain peptide pS2 gene product homolog , putative gastrointestinal growth factor xP1

GENE ID SPECIES
733152 Xenopus laevis
100170654 Felis catus
81751 Rattus norvegicus
7031 Homo sapiens
21784 Mus musculus
117270 Rattus norvegicus
780401 Sus scrofa
403491 Canis lupus familiaris
100301237 Bos taurus
101104450 Ovis aries
378509 Xenopus laevis
100358238 Oryctolagus cuniculus
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