TFF1 Protein (AA 25-84) (Fc Tag)

Catalog No. ABIN7275692

Product Details

Target: TFF1 (Trefoil Factor 1 (TFF1))

Protein Type: Recombinant

Protein Characteristics: AA 25-84

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TFF1 protein is labelled with Fc Tag.

Purpose: Human TFF1 Protein

Sequence: Glu25-Phe84

Characteristics: Recombinant Human TFF1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu25-Phe84.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: TFF1 (Trefoil Factor 1 (TFF1))

Alternative Name: TFF1 (TFF1 Products)

Synonyms: BCEI Protein, D21S21 Protein, HP1.A Protein, HPS2 Protein, pNR-2 Protein, pS2 Protein, Bcei Protein, PS2 Protein, bcei Protein, d21s21 Protein, hp1.a Protein, hps2 Protein, p1 Protein, p1-a Protein, pnr-2 Protein, ps2 Protein, tff1 Protein, xP1 Protein, xp1-L Protein, xp1 Protein, TFF1 Protein, Ps2 Protein, trefoil factor 1 Protein, trefoil factor 1 S homeolog Protein, trefoil factor 1, gene 2 S homeolog Protein, TFF1 Protein, Tff1 Protein, tff1.S Protein, tff1.2.S Protein, LOC100358238 Protein

Background: Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC.

Molecular Weight: 33.3 kDa. Due to glycosylation, the protein migrates to 40-45 kDa based on Tris-Bis PAGE result.

UniProt: P04155

Pathways: EGFR Signaling Pathway