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Cyclin D3 antibody (C-Term)

CCND3 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Sheep, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792167
  • Target See all Cyclin D3 (CCND3) Antibodies
    Cyclin D3 (CCND3)
    Binding Specificity
    • 33
    • 16
    • 11
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 113
    • 48
    • 37
    • 16
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Pig, Sheep, Guinea Pig
    Host
    • 99
    • 16
    Rabbit
    Clonality
    • 90
    • 25
    Polyclonal
    Conjugate
    • 52
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cyclin D3 antibody is un-conjugated
    Application
    • 85
    • 34
    • 32
    • 27
    • 26
    • 20
    • 15
    • 15
    • 10
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    CQEQIEAALR ESLREASQTS SSPAPKAPRG SSSQGPSQTS TPTDVTAIHL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CCND3. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CCND3
    Top Product
    Discover our top product CCND3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 292 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Cyclin D3 (CCND3)
    Alternative Name
    CCND3 (CCND3 Products)
    Synonyms
    zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
    Background
    CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
    Protein Interaction Partner: POLR3GL, TFIP11, CDKN1A, CDK6, CDK4, CDK5, MCM10, CDKN1B, CDK2, CDK11B, FAS, SIL1, EIF3K, ATF5, VDR, MAPK6, NME1, MYB, GC, ETV1, RBL2, POLD1, CDK14, APP, RB1, UBC, PPP1CC, PPP1CB, PPP1CA, NCOA2, MAF1, NPDC1, DMTF1, CRABP2, RARA, DTNBP1, AKAP8, EFEMP2, CAS
    Protein Size: 292
    Molecular Weight
    33 kDa
    Gene ID
    896
    NCBI Accession
    NM_001760, NP_001751
    UniProt
    P30281
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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