Centriolin antibody
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- Target See all Centriolin (CNTRL) Antibodies
- Centriolin (CNTRL)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Centriolin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- CEP110 Antibody detects endogenous levels of total CEP110
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CEP110
- Isotype
- IgG
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anti-Centriolin (CNTRL) (AA 2101-2325) antibody
CNTRL Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Centriolin (CNTRL) (AA 250-500) antibodyCNTRL Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Centriolin (CNTRL) (C-Term) antibodyCNTRL Reactivity: Human, Monkey WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Centriolin (CNTRL) (C-Term) antibodyCNTRL Reactivity: Human, Mouse, Rat WB, EIA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000 IHC 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- Centriolin (CNTRL)
- Alternative Name
- CEP110 (CNTRL Products)
- Synonyms
- CEP1 antibody, CEP110 antibody, FAN antibody, bA165P4.1 antibody, Cep1 antibody, Cep110 antibody, 6720467O09Rik antibody, AA968343 antibody, Cntrl antibody, IB3/5 antibody, Ma2a8 antibody, b2b1468Clo antibody, centriolin antibody, CNTRL antibody, Cntrl antibody
- Background
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Description: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Gene: CCP110
- Molecular Weight
- 113kDa
- Gene ID
- 9738
- UniProt
- O43303
- Pathways
- M Phase, SARS-CoV-2 Protein Interactome
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