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IPO13 antibody

IPO13 Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7115209
  • Target See all IPO13 Antibodies
    IPO13 (Importin 13 (IPO13))
    Reactivity
    • 19
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 19
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IPO13 antibody is un-conjugated
    Application
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    importin 13
    Isotype
    IgG
    Top Product
    Discover our top product IPO13 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    IPO13 (Importin 13 (IPO13))
    Alternative Name
    IPO13 (IPO13 Products)
    Synonyms
    3R23 antibody, CG 7212 antibody, CG7212 antibody, Dmel\\CG7212 antibody, Imp13 antibody, imp13 antibody, sd-5 antibody, DDBDRAFT_0205767 antibody, DDBDRAFT_0304414 antibody, DDB_0205767 antibody, DDB_0304414 antibody, DDBDRAFT_0191787 antibody, DDBDRAFT_0304413 antibody, DDB_0191787 antibody, DDB_0304413 antibody, IMP13 antibody, KAP13 antibody, LGL2 antibody, RANBP13 antibody, Kap13 antibody, Ranbp13 antibody, Lgl2 antibody, DKFZp459H088 antibody, cadmus antibody, importin 13 antibody, cdm antibody, IPO13 antibody, AFUA_5G08060 antibody, ANI_1_1340034 antibody, AOR_1_1272114 antibody, ipo13B antibody, ipo13A antibody, ipo13 antibody, Ipo13 antibody
    Background
    Synonyms:KIAA0724, RANBP13 Background:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.
    Molecular Weight
    97kd
    Gene ID
    9670
    UniProt
    O94829
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus
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