CLEC1A Protein (AA 73-269) (Fc Tag)
-
- Target See all CLEC1A Proteins
- CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 73-269
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC1A protein is labelled with Fc Tag.
- Purpose
- Mouse CLEC-1 Protein
- Sequence
- Gln73-Gln269
- Characteristics
- Recombinant Mouse CLEC-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln73-Gln269.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC1A Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))
- Alternative Name
- CLEC-1 (CLEC1A Products)
- Synonyms
- RGD1566110 Protein, CLEC1 Protein, 5930406N14Rik Protein, C-type lectin domain family 1, member A Protein, C-type lectin domain family 1 member A Protein, C-type lectin domain family 1, member a Protein, Clec1a Protein, CLEC1A Protein
- Background
- C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
- Molecular Weight
- 50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8BWY2
-