MPG antibody
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- Target See all MPG Antibodies
- MPG (N-Methylpurine-DNA Glycosylase (MPG))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MPG antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody ist KO validated.
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Grade
- KO Validated
- Immunogen
- Recombinant fusion protein of human MPG (NP_001015052.1).
- Isotype
- IgG
- Top Product
- Discover our top product MPG Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MPG (N-Methylpurine-DNA Glycosylase (MPG))
- Alternative Name
- MPG (MPG Products)
- Synonyms
- AAG antibody, ADPG antibody, APNG antibody, CRA36.1 antibody, MDG antibody, Mid1 antibody, PIG11 antibody, PIG16 antibody, anpg antibody, 9830006D05 antibody, AI326268 antibody, Aag antibody, zgc:162984 antibody, si:xx-187g17.9 antibody, MPG antibody, MPGR antibody, N-methylpurine DNA glycosylase antibody, N-methylpurine-DNA glycosylase antibody, si:xx-by187g17.9 antibody, MPG antibody, Mpg antibody, mpg antibody, si:xx-by187g17.9 antibody, CpB0526 antibody, gll2491 antibody
- Background
- Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase). Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.
- Molecular Weight
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Observed_MW: 37 kDa
Calculated_MW: 30 kDa/32 kDa
- Gene ID
- 4350
- UniProt
- P29372
- Pathways
- DNA Damage Repair
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