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FBXL5 antibody (AA 1-310)

FBXL5 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152485
  • Target See all FBXL5 Antibodies
    FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
    Binding Specificity
    • 16
    • 10
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-310
    Reactivity
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 3
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXL5 antibody is un-conjugated
    Application
    • 42
    • 28
    • 21
    • 21
    • 5
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human F-box/LRR-repeat protein 5 protein (1-310AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
    Alternative Name
    FBXL5 (FBXL5 Products)
    Synonyms
    fbxl5 antibody, MGC53238 antibody, FBXL5 antibody, FBL4 antibody, FBL5 antibody, FLR1 antibody, Fbl4 antibody, Fir4 antibody, wu:fb52d06 antibody, F-box and leucine rich repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 S homeolog antibody, F-box and leucine-rich repeat protein 5 L homeolog antibody, F-box and leucine-rich repeat protein 5 antibody, FBXL5 antibody, fbxl5.S antibody, fbxl5.L antibody, fbxl5 antibody, Fbxl5 antibody
    Background

    Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

    Aliases: F box and leucine rich repeat protein 5 antibody, F box protein FBL5 antibody, F box/LRR repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 antibody, F-box protein FBL4/FBL5 antibody, F-box/LRR-repeat protein 5 antibody, FBL4 antibody, FBL5 antibody, FBXL5 antibody, FBXL5_HUMAN antibody, FLR1 antibody, p45SKP2 like protein antibody, p45SKP2-like protein antibody

    UniProt
    Q9UKA1
    Pathways
    Transition Metal Ion Homeostasis
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