POLH antibody
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- Target See all POLH Antibodies
- POLH (Polymerase (DNA Directed), eta (POLH))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLH antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human DNA polymerase eta (NP_006493.1).
- Isotype
- IgG
- Top Product
- Discover our top product POLH Primary Antibody
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anti-Polymerase (DNA Directed), eta (POLH) (AA 408-609) antibody
POLH Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 20-320) antibodyPOLH Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (Internal Region) antibodyPOLH Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 1-713) antibodyPOLH Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 1-713) antibodyPOLH Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH Reactivity: Human, Mouse, Rat WB, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 157-361) antibodyPOLH Reactivity: Human, Rat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- POLH (Polymerase (DNA Directed), eta (POLH))
- Alternative Name
- DNA polymerase eta (POLH Products)
- Synonyms
- POLH antibody, fc50a12 antibody, wu:fc50a12 antibody, zgc:136881 antibody, zgc:152642 antibody, RAD30 antibody, RAD30A antibody, XP-V antibody, XPV antibody, polymerase (DNA directed), eta S homeolog antibody, DNA polymerase eta antibody, polymerase (DNA directed), eta antibody, putative DNA polymerase eta antibody, polymerase (DNA directed), eta (RAD 30 related) antibody, polh.S antibody, POLH antibody, polh antibody, Tb10.70.6190 antibody, LINJ_21_0690 antibody, Polh antibody, LOC100443019 antibody
- Background
- This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 70 kDa
Calculated_MW: 46 kDa/78 kDa
- Gene ID
- 5429
- UniProt
- Q9Y253
- Pathways
- DNA Damage Repair
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