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H2AFB1 antibody (AA 1-115)

H2AFB1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7155373
  • Target See all H2AFB1 Antibodies
    H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
    Binding Specificity
    • 4
    • 1
    • 1
    AA 1-115
    Reactivity
    Human
    Host
    • 6
    Rabbit
    Clonality
    • 6
    Polyclonal
    Conjugate
    • 2
    • 2
    • 1
    • 1
    This H2AFB1 antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
    Alternative Name
    H2AFB1 (H2AFB1 Products)
    Synonyms
    H2A.Bbd antibody, H2A histone family member B1 antibody, H2AFB1 antibody
    Background

    Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.

    Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody

    UniProt
    P0C5Y9
    Pathways
    Telomere Maintenance
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