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Mesothelin antibody

MSLN Reactivity: Human, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7008610
  • Target See all Mesothelin (MSLN) Antibodies
    Mesothelin (MSLN)
    Reactivity
    • 88
    • 24
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 74
    • 25
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 73
    • 30
    • 2
    Polyclonal
    Conjugate
    • 67
    • 12
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Mesothelin antibody is un-conjugated
    Application
    • 68
    • 51
    • 24
    • 21
    • 12
    • 10
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MSLN (NP_001170826.1).
    Isotype
    IgG
    Top Product
    Discover our top product MSLN Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Mesothelin (MSLN)
    Alternative Name
    MSLN (MSLN Products)
    Synonyms
    MPF antibody, SMRP antibody, MSLN antibody, mesothelin antibody, MSLN antibody, Msln antibody, LOC611363 antibody, LOC100524016 antibody
    Background
    This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    Gene ID
    10232
    UniProt
    Q13421
    Pathways
    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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