CRLF2 Protein (Fc Tag)
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- Target See all CRLF2 Proteins
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CRLF2 protein is labelled with Fc Tag.
- Sequence
- Gly25-Lys231
- Purity
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human TSLP (R127A, R130A) at 1μg/ml (100μl/Well). Dose response curve for Human TSLPR, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. See testing image for detail.
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Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) protein (His tag)
CRLF2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)CRLF2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) (Active) protein (Fc Tag)CRLF2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (Active) protein (Fc Tag)CRLF2 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) protein (GST tag)CRLF2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cytokine Receptor-Like Factor 2 (CRLF2) protein (His tag)CRLF2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) protein (Fc Tag)CRLF2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)Crystallography grade CRLF2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 253-371) protein (His tag)Crystallography grade CRLF2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 20-232) protein (His tag)Crystallography grade CRLF2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Alternative Name
- TSLPR (CRLF2 Products)
- Synonyms
- CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
- Background
- TSLP receptor, TSLPR, CRL2, CRLF2Y, CRLF2, IL-XR, p2RY8/CRLF2 fusion, CRLF2,Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
- Molecular Weight
- 50.8 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
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