ATG3 antibody
-
- Target See all ATG3 Antibodies
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
-
Reactivity
- Human, Mouse
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This ATG3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein G.
- Immunogen
- This ATG3 antibody is generated from a mouse immunized with recombinant protein of human ATG3.
- Clone
- 7C2
- Isotype
- IgG1
- Top Product
- Discover our top product ATG3 Primary Antibody
-
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 Reactivity: Human, Monkey WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 7A1D1 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-314) antibodyATG3 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 Reactivity: Human, Rat, Dog, Monkey WB, IF, FACS Host: Mouse Monoclonal 3C6 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 Reactivity: Human, Rat, Dog, Monkey WB, IF, FACS Host: Mouse Monoclonal 3G3 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (Middle Region) antibodyATG3 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 168-197), (C-Term) antibodyATG3 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB7459 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibodyATG3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1G3 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibody (HRP)ATG3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal HRP
anti-ATG3 Autophagy Related 3 (ATG3) antibody (Alkaline Phosphatase (AP))ATG3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal Alkaline Phosphatase (AP)
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
- Alternative Name
- ATG3 (ATG3 Products)
- Synonyms
- atg3 antibody, im:6910145 antibody, wu:fb15g12 antibody, zgc:64156 antibody, APG3 antibody, APG3-LIKE antibody, APG3L antibody, PC3-96 antibody, 2610016C12Rik antibody, Apg3l antibody, Atg3l antibody, PIG-1 antibody, Pig1 antibody, ATATG3 antibody, K11J9.1 antibody, K11J9_1 antibody, autophagy related 3 antibody, autophagy 3 (APG3) antibody, similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy antibody, atg3 antibody, ATG3 antibody, Atg3 antibody
- Background
-
Synonyms: APG3, APG3L, PC3-96, APG3-LIKE, Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, hApg3, Protein PC3-96, ATG3
Background: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
- Gene ID
- 64422
- UniProt
- Q9NT62
- Pathways
- Autophagy
-
