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Aurora Kinase C antibody (AA 12-143)

Name: Aurora Kinase C antibody (AA 12-143)
Brand: antibodies-online
SKU: ABIN7145083
Price: 328.9 USD
Availability: InStock

AURKC Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

Western Blot Positive WB detected in: A375 whole cell lysate All lanes: AURKC antibody at 3. (Aurora Kinase C antibody (AA 12-143))

Immunohistochemistry of paraffin-embedded human melanoma using ABIN7145083 at dilution of 1:100 (Aurora Kinase C antibody (AA 12-143))

IHC

Immunohistochemistry of paraffin-embedded human liver cancer using ABIN7145083 at dilution of 1:100 (Aurora Kinase C antibody (AA 12-143))

IHC

Immunofluorescent analysis of Hela cells using ABIN7145083 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) (Aurora Kinase C antibody (AA 12-143))

4 images

Catalog No. ABIN7145083

Datasheet as PDF

Target See all Aurora Kinase C (AURKC) Antibodies

Aurora Kinase C (AURKC)
Binding Specificity
9

9

9

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1
AA 12-143
Reactivity
58

22

17

1

1

1

1

1

1

1
Human
Host
57

2

1
Rabbit
Compatible Secondaries
Clonality
60
Polyclonal
Conjugate
32

5

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1
This Aurora Kinase C antibody is un-conjugated
Application
53

30

19

13

8

3

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity

Human

Purification

>95%, Protein G purified

Immunogen

Recombinant Human Aurora kinase C protein (12-143AA)

Isotype

IgG
anti-Aurora Kinase C (AURKC) (AA 3-38) antibody
AURKC Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Aurora Kinase C (AURKC) (AA 3-38), (N-Term) antibody
AURKC Reactivity: Human WB Host: Rabbit Polyclonal RB6507 unconjugated

anti-Aurora Kinase C (AURKC) (AA 115-145) antibody
AURKC Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB6822 unconjugated

anti-Aurora Kinase C (AURKC) antibody
AURKC Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Aurora Kinase C (AURKC) (C-Term) antibody
AURKC Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB0881 unconjugated

anti-Aurora Kinase C (AURKC) (AA 1-30), (N-Term) antibody
AURKC Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB6505 unconjugated

anti-Aurora Kinase C (AURKC) (N-Term) antibody
AURKC Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Aurora Kinase C (AURKC) (AA 5-237) antibody
AURKC Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Aurora Kinase C (AURKC) (AA 115-145) antibody
AURKC Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Aurora Kinase C (AURKC) (AA 1-30) antibody
AURKC Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions

For Research Use only
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C,-80 °C

Storage Comment

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

Aurora Kinase C (AURKC)

Alternative Name

AURKC (AURKC Products)

Synonyms

AURKC antibody, AIE2 antibody, AIK3 antibody, ARK3 antibody, AurC antibody, SPGF5 antibody, STK13 antibody, aurora-C antibody, AIE1 antibody, ARK-3 antibody, IAK3 antibody, Stk13 antibody, aurora kinase C antibody, AURKC antibody, Aurkc antibody

Background

Background: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at \\\'Ser-10\\\' and \\\'Ser-28\\\'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at \\\'Ser-228\\\'.
Aliases: AURKC antibody, AIE 2 antibody, Aie1 antibody, AIE2 antibody, AIK 3 antibody, AIK3 antibody, ARK 3 antibody, ARK-3 antibody, ARK3 antibody, Aur C antibody, AurC antibody, Aurkc antibody, AURKC_HUMAN antibody, aurora 3 antibody, Aurora C antibody, Aurora kinase C antibody, aurora related kinase 3 antibody, Aurora-related kinase 3 antibody, Aurora/Ipl1 related kinase 3 antibody, Aurora/Ipl1-related kinase 3 antibody, Aurora/Ipl1/Eg2 protein 2 antibody, EC 2.7.11.1 antibody, Serine threonine protein kinase 13 antibody, serine/threonine kinase 13 (aurora/IPL1 like) antibody, serine/threonine protein kinase aurora C antibody, Serine/threonine-protein kinase 13 antibody, Serine/threonine-protein kinase aurora-C antibody, SPGF5 antibody, STK13 antibody

UniProt

Q9UQB9

Pathways

Cell Division Cycle, Maintenance of Protein Location