Aurora Kinase C antibody (AA 115-145)

Catalog No. ABIN3030079

This Rabbit Polyclonal antibody specifically detects Aurora Kinase C in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Aurora Kinase C antibody (AA 115-145) (ABIN3030079)

Target: Aurora Kinase C (AURKC)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora Kinase C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Aurora Kinase C Antibody

Binding Specificity: AA 115-145

Purpose: Aurora-C Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 115-145 from the human protein was used as the immunogen for this Aurora-C antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Aurora-C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Aurora-C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Alternative Name: Aurora-C

Background: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

UniProt: Q9UQB9

Pathways: Cell Division Cycle, Maintenance of Protein Location