Concentration Definition: by UV absorbance at 280 nm
Immunogen
This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 686-698 of Human AP3D1.
AP3D1
Reactivity: Human
WB, ELISA, IP
Host: Goat
Polyclonal
unconjugated
Application Notes
This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 130 kDa in size corresponding to AP3D1 by western blotting in the appropriate cell lysate or extract. Multiple isoforms exist for this protein.
Restrictions
For Research Use only
Format
Liquid
Concentration
1.6 mg/mL
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Zheng, Saunders, Sorensen, Waxmonsky, Conner: "Notch signaling from the endosome requires a conserved dileucine motif." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 297-307, (2013) (PubMed).
Concepcion, Flores-Garcuia, Hamilton: "Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing." in: PLoS genetics, Vol. 5, Issue 5, pp. e1000484, (2009) (PubMed).
Target
AP3D1
(Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))
AP3D1 (also known as Delta-adaptin 3, AP-3 complex delta subunit and Delta-adaptin) is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles. Synonyms: AP-3 complex subunit delta-1 Adapter-related protein complex 3 subunit delta-1 AP-3 complex subunit delta Delta-adaptin