LCMT2 antibody (N-Term)
LCMT2
Reactivity: Human, Rat, Mouse
WB, ELISA, IHC (p), IF
Host: Rabbit
Polyclonal
unconjugated
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- Target See all LCMT2 Antibodies
- LCMT2 (Leucine Carboxyl Methyltransferase 2 (LCMT2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LCMT2 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificity
- TYW4 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW4 are known to exist, this antibody will detect only the long isoform.
- Purification
- TYW4 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- TYW4 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human TYW4. The immunogen is located within the first 50 amino acids of TYW4.
- Isotype
- IgG
- Top Product
- Discover our top product LCMT2 Primary Antibody
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anti-Leucine Carboxyl Methyltransferase 2 (LCMT2) (AA 506-555) antibody
LCMT2 Reactivity: Human, Cow, Dog, Horse, Pig, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Leucine Carboxyl Methyltransferase 2 (LCMT2) (C-Term) antibodyLCMT2 Reactivity: Human, Rat, Cow, Dog, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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TYW4 antibody can be used for detection of TYW4 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- TYW4 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- TYW4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- LCMT2 (Leucine Carboxyl Methyltransferase 2 (LCMT2))
- Alternative Name
- TYW4 (LCMT2 Products)
- Synonyms
- si:ch211-194d6.3 antibody, wu:fi38a08 antibody, PPM2 antibody, TYW4 antibody, D330024M17 antibody, Tyw4 antibody, leucine carboxyl methyltransferase 2 antibody, hypothetical protein antibody, tRNA methyltransferase antibody, ANI_1_1244164 antibody, AOR_1_496094 antibody, PTRG_08920 antibody, BDBG_01006 antibody, MCYG_03718 antibody, MGYG_03321 antibody, PGTG_17062 antibody, lcmt2 antibody, CAALFM_C101150CA antibody, LCMT2 antibody, Lcmt2 antibody
- Background
- TYW4 Antibody: TYW4 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW4 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
- Gene ID
- 9836
- NCBI Accession
- NP_055608
- UniProt
- O60294
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