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anti-Mouse (Murine) AMFR Antibodies:
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Human Polyclonal AMFR Primary Antibody for EIA, WB - ABIN950395
Joshi, Li, Nabi: A role for KAI1 in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase. in The Journal of biological chemistry 2010
Show all 5 references for ABIN950395
Human Polyclonal AMFR Primary Antibody for FACS, IHC (p) - ABIN388938
Huang, Xie, Raz: Identification of an upstream region that controls the transcription of the human autocrine motility factor receptor. in Biochemical and biophysical research communications 1995
Show all 3 references for ABIN388938
Human Polyclonal AMFR Primary Antibody for EIA, IHC (p) - ABIN357584
Araki, Shimura, Yajima, Tsutsumi, Suzuki, Okada, Kobayashi, Raz, Kuwano: Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8. in The Journal of biological chemistry 2009
Show all 2 references for ABIN357584
Human Polyclonal AMFR Primary Antibody for Func, IHC - ABIN4280243
Lucarelli, Galleggiante, Rutigliano, Sanguedolce, Cagiano, Bufo, Lastilla, Maiorano, Ribatti, Giglio, Serino, Vavallo, Bettocchi, Selvaggi, Battaglia, Ditonno: Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma. in Oncotarget 2015
Show all 2 references for ABIN4280243
Cow (Bovine) Polyclonal AMFR Primary Antibody for WB - ABIN2775669
Lehner, Sanderson: A protein interaction framework for human mRNA degradation. in Genome research 2004
gp78 plays a critical role in protecting against ER stress in liver
Gp78, an E3 ubiquitin ligase (show MUL1 Antibodies) acts as a gatekeeper suppressing nonalcoholic steatohepatitis (NASH (show SAMSN1 Antibodies)) and liver cancer.
The ubiquitin ligase (show RNF123 Antibodies) gp78, known for its role in protein quality control, is critical for unglycosylated PrP ubiquitylation and degradation.
we consistently observe involvement of gp78 in Insig-1 (show INSIG1 Antibodies) degradation, we find no substantive evidence to support roles for either gp78 or TRC8 (show RNF139 Antibodies) in the robust sterol-accelerated degradation of HMG-CoA reductase (show HMGCR Antibodies)
Ablation of gp78 in liver improves hyperlipidemia and insulin (show INS Antibodies) resistance by inhibiting SREBP to decrease lipid biosynthesis.
Palmitoylation of RING finger (show PCGF1 Antibodies) cysteines therefore regulates gp78 distribution to the peripheral ER
AMFR is involved in the process of learning and memory in the central nervous system.
KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase
Gp78 promotes SOD1 (show SOD1 Antibodies) and ataxin-3 (show ATXN3 Antibodies) degradation in endoplasmic reticulum.
cytoplasmic protein (show BLZF1 Antibodies) mouse p97 (show EIF4G2 Antibodies)(mp97) participates in the formation of a ternary complex containing mouse autocrine motility factor receptor (mAMFR), mp97, and peptide N-glycanase
the receptor molecule for AMF/NLK/MF in leukemic differentiation is not gp78
AMFR expression is significantly reduced in plasma from osteoporosis patients.
Catalytic inactivation of MGRN1 (show MGRN1 Antibodies) results in elevated levels of GP78 and a consequential increase in the initiation of mitophagy.
Authors conclude that the Hrd1 (show SYVN1 Antibodies) complex forms an essential retrotranslocation module that is evolutionarily conserved, but the mammalian ERAD system uses additional ubiquitin ligases to assist Hrd1 (show SYVN1 Antibodies) during retrotranslocation.
Downregulation of AMFR induced cell cycle arrest at the G0/G1 phase, and increased apoptosis of the THP1 (show GLI2 Antibodies) cells.
The authors identify USP13 (show USP13 Antibodies) as a gp78-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A (show UBL4A Antibodies) to maintain the functionality of Bag6 (show BAT3 Antibodies).
Data show that autocrine motility factor receptor (AMFR) and NOTCH1 (show NOTCH1 Antibodies) protein are the direct target genes of microRNA miR (show MLXIP Antibodies)-139-5p in colorectal cancer (CRC (show CALR Antibodies)).
gp78 elongates polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains.
Our data uncovers a previously unknown functional link between gp78 and TRIM25 (show TRIM25 Antibodies) and provides mechanistic insight into gp78-mediated protein ubiquitylation.
The ubiquitin ligase gp78, known for its role in protein quality control, is critical for unglycosylated PrP (show C4BPA Antibodies) ubiquitylation and degradation.
High AMFR expression is associated with invasion depth and lymph node metastasis in gastric cancer.
This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
autocrine motility factor receptor
, autocrine motility factor receptor, amfr
, autocrine motility factor receptor amfr
, autocrine motility factor receptor, isoform 2-like
, AMF receptor
, E3 ubiquitin-protein ligase AMFR
, RING finger protein 45