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anti-Human DNAJB9 Antibodies:
anti-Mouse (Murine) DNAJB9 Antibodies:
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Human Monoclonal DNAJB9 Primary Antibody for IF, ELISA - ABIN517794
van Galen, Kreso, Mbong, Kent, Fitzmaurice, Chambers, Xie, Laurenti, Hermans, Eppert, Marciniak, Goodall, Green, Wouters, Wienholds, Dick: The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress. in Nature 2014
Human Polyclonal DNAJB9 Primary Antibody for ELISA, WB - ABIN4333303
Ushioda, Hoseki, Nagata: Glycosylation-independent ERAD pathway serves as a backup system under ER stress. in Molecular biology of the cell 2013
Human Polyclonal DNAJB9 Primary Antibody for ICC, IF - ABIN4333305
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Study reports that the endoplasmic reticulum luminal co-chaperone ERdj4/DNAJB9 is a selective IRE1 (show ERN1 Antibodies) repressor that promotes a complex between the luminal Hsp70 (show HSP70 Antibodies) BiP (show GDF10 Antibodies) and the luminal stress-sensing domain of IRE1alpha (show ERN1 Antibodies).
these results demonstrate that DNAJB9 is a downstream target of p53 (show TP53 Antibodies) that belongs to the group of negative feedback regulators of p53 (show TP53 Antibodies).
ERdj4 and ERdj5 (show DNAJC10 Antibodies) promote turnover of misfolded SP-C (show SFTPC Antibodies) and this activity is dependent on their ability to stimulate BiP (show GDF10 Antibodies) ATPase (show DNAH8 Antibodies) activity.
ERdj4 gene trap mice showed non-specific hypergammaglobulinemia and gene trap B (show SSR2 Antibodies) cells exhibited increased proliferation, survival and isotype switching in response to LPS (show TLR4 Antibodies) stimulation.
Deficiency of the BiP (show HSPA5 Antibodies) cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects.
directly link ERdj4 to the ERAD machinery and suggest a model in which ERjd4 could help recruit clients from throughout the ER to ERAD sites
DnaJ (show DNAJA2 Antibodies) homolog, which stimulates ATPase (show DNAH8 Antibodies) activity of BiP (show HSPA5 Antibodies) and is induced by endoplasmic reticulum stress
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis.
dnaJ homolog subfamily B member 9
, endoplasmic reticulum DnaJ homolog 4
, microvascular endothelial differentiation gene 1 protein
, DNA j protein b9
, microvascular endothelial differentiation gene 1
, dnaJ homolog, subfamily b, member 9