Browse our anti-ERN1 (ERN1) Antibodies

Full name:
anti-Endoplasmic Reticulum To Nucleus Signaling 1 Antibodies (ERN1)
On www.antibodies-online.com are 210 Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) Antibodies from 22 different suppliers available. Additionally we are shipping ERN1 Kits (36) and ERN1 Proteins (15) and many more products for this protein. A total of 275 ERN1 products are currently listed.
Synonyms:
9030414B18Rik, AI225830, C85377, Ern1, hIRE1p, IRE1, IRE1a, Ire1alpha, Ire1b, IRE1P, RGD1559716
list all antibodies Gene Name GeneID UniProt
ERN1 78943 Q9EQY0
ERN1 2081 O75460
ERN1 498013  

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anti-Mouse (Murine) ERN1 Antibodies:

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anti-Rat (Rattus) ERN1 Antibodies:

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Top referenced anti-ERN1 Antibodies

  1. Human Polyclonal ERN1 Primary Antibody for ELISA, ICC - ABIN250706 : Lipson, Fonseca, Ishigaki, Nguyen, Foss, Bortell, Rossini, Urano: Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. in Cell metabolism 2006 (PubMed)
    Show all 140 references for 250706

  2. Human Polyclonal ERN1 Primary Antibody for ICC, IF - ABIN250711 : Kubota, Lee, Tsuchiya, Young, Everett, Martinez-Mier, Snead, Nguyen, Urano, Bartlett: Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation. in The Journal of biological chemistry 2005 (PubMed)
    Show all 17 references for 250711

  3. Human Monoclonal ERN1 Primary Antibody for ELISA, IHC (p) - ABIN1999391 : Trentmann: ERN1, a novel ethylene-regulated nuclear protein of Arabidopsis. in Plant molecular biology 2000 (PubMed)
    Show all 3 references for 1999391

  4. Human Monoclonal ERN1 Primary Antibody for IHC, ELISA - ABIN969116 : Huang, Tan, Yoshida, Mori, Ma, Yen: Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress. in Molecular and cellular biology 2005 (PubMed)
    Show all 3 references for 969116

  5. Human Polyclonal ERN1 Primary Antibody for IF (p), IHC (p) - ABIN1387531 : Xu, Su, Song, Shi, Fu, Hu, Xia, Song, Song: Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release. in Chemical research in toxicology 2015 (PubMed)
    Show all 2 references for 1387531

  6. Human Polyclonal ERN1 Primary Antibody for ELISA, ICC - ABIN250707 : Luo, He, Zhang, Yu, Chen, Xu, Tang, Urano, Min: AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for 250707

  7. Human Polyclonal ERN1 Primary Antibody for ELISA, WB - ABIN316350 : Yokouchi, Hiramatsu, Hayakawa, Okamura, Du, Kasai, Takano, Shitamura, Shimada, Yao, Kitamura: Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response. in The Journal of biological chemistry 2008 (PubMed)

  8. Human Polyclonal ERN1 Primary Antibody for IHC (fro), IF - ABIN318703 : Zhang, Kaufman: Signaling the unfolded protein response from the endoplasmic reticulum. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against ERN1 Interaction Partners

Mouse (Murine) Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) interaction partners

  1. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

  2. defective autophagy in intestinal epithelial cells (IECs) may predispose to Crohn's disease ileitis via impaired clearance of IRE1alpha aggregates during ER stress at this site.

  3. The findings indicate that IRE1-XBP1 (show XBP1 Antibodies) downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  4. the ABL (show ABL1 Antibodies) family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  5. We reveal distinct binding affinities between the binary and ternary complexes thus formed, that suggest a preference for the PERK (show EIF2AK3 Antibodies) signaling branch under stress, and a predilection for the GRP78 (show HSPA5 Antibodies)-UPR sensor complex formation upon stressor removal. These results imply a gated UPR mechanism that tunes the overall cellular behavior to the accumulation of unfolded proteins.

  6. Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs.

  7. Ire1alpha-Xbp1s and associated molecular targets link ER stress in arcuate Pomc (show POMC Antibodies) neurons to aspects of normal energy and glucose homeostasis.

  8. heat stress simultaneously activates both the unfolded protein response (UPR) and autophagy, followed by the activation of a negative feedback system in UPR by modulating the responses related to the IRE1alpha-XBP-1 (show XBP1 Antibodies) axis.

  9. this study shows that IRE1alpha is a critical switch governing M1-M2 macrophage polarization and energy balance in obesity

  10. Findings indicate that PERK (show EIF2AK3 Antibodies) kinase-activating transcription factor 4 (ATF4 (show ATF4 Antibodies)) pathway affected the efficiency of X-box binding protein 1 (XBP1 (show XBP1 Antibodies)) mRNA splicing by regulating inositol-requiring enzyme 1alpha (IRE1alpha) expression.

Human Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) interaction partners

  1. Results of this investigation demonstrate that inhibition of IRE1 signaling enzyme function affects the expression of NRIP1 (show NRIP1 Antibodies), EBBP (show TRIM16 Antibodies), ESRRA (show ESRRA Antibodies), E2IG5 (show FAM162A Antibodies), PGRMC2 (show PGRMC2 Antibodies), and SLC39A6 (show SLC39A6 Antibodies) genes in U87 glioma cells in gene specific manner and these changes possibly contribute to the suppression of the cell proliferation. Most of these genes are regulated by hypoxia and preferentially through IRE1 signaling pathway of endoplasmic reticulum stress

  2. IRE1alpha was shown to cleave miR (show MLXIP Antibodies)-150 and thereby to release the suppressive effect that miR (show MLXIP Antibodies)-150 exerted on alphaSMA (show ACTA2 Antibodies) expression through c-Myb (show MYB Antibodies). Inhibition of IRE1alpha was also demonstrated to block endoplasmic reticulum expansion through an XBP-1 (show XBP1 Antibodies)-dependent pathway.

  3. IRE-1 has an ancient function as a cytoplasmic sentinel that activates p38 (show CRK Antibodies) and SKN-1(Nrf2 (show GABPA Antibodies)). csteine modifications induced by ROS (show ROS1 Antibodies) signals can direct proteins to adopt unexpected functions and may coordinate many cellular processes.

  4. The findings indicate that IRE1-XBP1 (show XBP1 Antibodies) downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  5. Western blot analysis of subcutaneously implanted AsPC-1 and BxPC-3 tumors as well as orthotopically implanted Panc-1 tumors demonstrated upregulation of BIP (show GDF10 Antibodies), CHOP (show DDIT3 Antibodies), and IRE1alpha expression in the tumor lysates from penfluridol-treated mice as compared to tumors from control mice

  6. the ABL (show ABL1 Antibodies) family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  7. Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK (show EIF2AK3 Antibodies) and IRE1 signalings

  8. IRE1 is involved in multivesicular body information during endoplasmic reticulum stress.

  9. Comparison of this structure with other existing structures of IRE1alpha and integration of our extensive structure activity relationship (SAR (show SARDH Antibodies)) data has led us to formulate a model to rationalize how ATP-binding site ligands are able to control the IRE1alpha oligomeric state and subsequent RNase domain activity

  10. Our data indicate that reduced response of IRE1alpha/Xbp-1 (show XBP1 Antibodies) signaling pathway to bortezomib may contribute to drug resistance in myeloma cells

ERN1 Antigen Profile

Antigen Summary

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Alternative names and synonyms associated with ERN1

  • endoplasmic reticulum (ER) to nucleus signalling 1 (Ern1) antibody
  • endoplasmic reticulum (ER) to nucleus signalling 2 (Ern2) antibody
  • endoplasmic reticulum to nucleus signaling 1 (ERN1) antibody
  • endoplasmic reticulum to nucleus signaling 1 (Ern1) antibody
  • endoplasmic reticulum to nucleus signalling 1 (LOC100357346) antibody
  • 9030414B18Rik antibody
  • AI225830 antibody
  • C85377 antibody
  • Ern1 antibody
  • hIRE1p antibody
  • IRE1 antibody
  • IRE1a antibody
  • Ire1alpha antibody
  • Ire1b antibody
  • IRE1P antibody
  • RGD1559716 antibody

Protein level used designations for ERN1

endoplasmic reticulum-to-nucleus signaling 1 , inositol-requiring 1 alpha , inositol-requiring protein 1 , ire1-alpha , serine/threonine-protein kinase/endoribonuclease IRE1 , endoplasmic reticulum-to-nucleus signaling 2 , inositol-requiring 1 (Yeast homologue) , inositol-requiring 1 beta , inositol-requiring protein 2 , ire1-beta , mIre1 , serine/threonine-protein kinase/endoribonuclease IRE2 , ER to nucleus signalling 1 , inositol-requiring 1 , inositol-requiring enzyme 1 , protein kinase/endoribonuclease , endoplasmic reticulum (ER) to nucleus signalling 1 , endoplasmic reticulum to nucleus signalling 1

GENE ID SPECIES
78943 Mus musculus
26918 Mus musculus
2081 Homo sapiens
498013 Rattus norvegicus
100733391 Cavia porcellus
100510978 Sus scrofa
610766 Canis lupus familiaris
524719 Bos taurus
771230 Gallus gallus
101102746 Ovis aries
100357346 Oryctolagus cuniculus
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