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Human Monoclonal TRAT1 Primary Antibody for FACS - ABIN125716
Kirchgessner, Dietrich, Scherer, Isomäki, Korinek, Hilgert, Bruyns, Leo, Cope, Schraven: The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. in The Journal of experimental medicine 2001
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Human Monoclonal TRAT1 Primary Antibody for FACS, IP - ABIN94489
Tedoldi, Paterson, Hansmann, Natkunam, Rüdiger, Angelisova, Du, Roberton, Roncador, Sanchez, Pozzobon, Masir, Barry, Pileri, Mason, Marafioti, Horejsí: Transmembrane adaptor molecules: a new category of lymphoid-cell markers. in Blood 2005
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Human Monoclonal TRAT1 Primary Antibody for ICFC - ABIN2666376
Bruyns, Marie-Cardine, Kirchgessner, Sagolla, Shevchenko, Mann, Autschbach, Bensussan, Meuer, Schraven: T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane. in The Journal of experimental medicine 1998
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TRIM proteins trim the balance of homoeostasis by modulating various biological pathways through protein-protein interactions.
MG53/TRIM72 (show TRIM72 Antibodies) protein can be directly applied as a therapeutic agent to increase membrane repair capacity of many cell types.
TRIM acts to chaperone CTLA-4 (show CTLA4 Antibodies) transport to the cell surface; this function would be required to account for the phenotypic and functional properties of CD8 (show CD8A Antibodies)(+) Tregs.
TRIM is dispensable for T-cell development and peripheral immune functions.
TRIM and Src homology domain-containing tyrosine phosphatase 2-interacting transmembrane adaptor protein (SIT) regulate cell fate of developing thymocytes and are essential regulators of central tolerance.
Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells (By similarity).
T cell receptor associated transmembrane adaptor 1
, T cell receptor interacting molecule
, T-cell receptor interacting molecule
, T-cell receptor-associated transmembrane adapter 1
, T-cell receptor-interacting molecule