TRIM antibody (PE)

Catalog No. ABIN536099

Product Details anti-TRIM Antibody (PE)

Target: TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIM antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against partial recombinant TRAT1.

Specificity: This antibody reacts with T cell receptor-interacting molecule (TRIM), a 30 KDa adaptor protein expressed by T cells.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to partial human TRAT1.

Clone: TRIM-04

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry (1:50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-TRIM antibody (PE) (ABIN536099)

Tedoldi, Paterson, Hansmann, Natkunam, Rüdiger, Angelisova, Du, Roberton, Roncador, Sanchez, Pozzobon, Masir, Barry, Pileri, Mason, Marafioti, Horejsí: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).

Simeoni, Smida, Posevitz, Schraven, Lindquist: "Right time, right place: the organization of membrane proximal signaling." in: Seminars in immunology, Vol. 17, Issue 1, pp. 35-49, (2004) (PubMed).

Kirchgessner, Dietrich, Scherer, Isomäki, Korinek, Hilgert, Bruyns, Leo, Cope, Schraven: "The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain." in: The Journal of experimental medicine, Vol. 193, Issue 11, pp. 1269-84, (2001) (PubMed).

Target Details for TRIM

Target: TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))

Alternative Name: TRAT1 / TRIM (TRAT1 Products)

Synonyms: TCRIM antibody, TRIM antibody, C030046M14Rik antibody, Tcrim antibody, Trim antibody, T cell receptor associated transmembrane adaptor 1 antibody, T-cell receptor associated transmembrane adaptor 1 antibody, TRAT1 antibody, Trat1 antibody

Gene ID: 50852

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway