Browse our anti-GNAO1 (GNAO1) Antibodies

Full name:
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O Antibodies (GNAO1)
On www.antibodies-online.com are 70 Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1) Antibodies from 13 different suppliers available. Additionally we are shipping GNAO1 Proteins (19) and many more products for this protein. A total of 95 GNAO1 products are currently listed.
Synonyms:
alphaO, AW050213, G-ALPHA-o, Galphao, Gnao, gnao1, gnao1-A, RATBPGTPC, wu:fq26h05, XGalpha01, zgc:73315
list all antibodies Gene Name GeneID UniProt
GNAO1 2775 P09471
GNAO1 50664 P59215
GNAO1 14681 P18872

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Top referenced anti-GNAO1 Antibodies

  1. Cow (Bovine) Polyclonal GNAO1 Primary Antibody for IHC, WB - ABIN2786202 : Won, Park, Ju, Kim, Suh-Kim, Ghil: The alpha subunit of Go interacts with promyelocytic leukemia zinc finger protein and modulates its functions. in Cellular signalling 2008 (PubMed)

More Antibodies against GNAO1 Interaction Partners

Human Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1) interaction partners

  1. Study identified distinct biochemical mechanisms of pathogenic human GNAO1 mutations that may improve the understanding of the heterogeneous clinical spectrum of GNAO1-associated epilepsy and movement disorders. Furthermore, these results also carry significant implications for personalized therapeutics in GNAO1 encephalopathies.

  2. The neurological phenotypes associated with GNAO1 mutations appear to lie on a spectrum, and it is possible that the c.607G>A (p.Gly203Arg) variant characterizes a phenotype with both severe epilepsy and chorea.

  3. authors report 2 cases of brothers with a severe movement disorder and hypotonia without epilepsy who have been confirmed by whole exome sequencing to have a novel mutation in GNAO1

  4. Phenotypic spectrum of novel GNAO1 variants in four unrelated female patients included epileptic encephalopathy and involuntary movements with severe developmental delay.

  5. GNAO1 is a disease-causing gene for the autosomal dominant form of early infantile epileptic encephalopathy. The novel pathogenic variant identified in should contribute to our understanding of the expanding spectrum of infantile-onset epilepsy.

  6. Endothelial cells in capillary malformations are enriched for GNAQ mutations and are likely responsible for the pathophysiology underlying capillary malformation.

  7. Galphao-R243H has a mild decrease in nucleotide affinity that causes rapid nucleotide turnover and subsequent hyperactivity in cancer

  8. Genetic variants of BCL2 (show BCL2 Antibodies), GNAO1, and CHD2 (show CHD2 Antibodies) are associated with non-obstructive azoospermia risk.

  9. the present study is the first to demonstrate that GNAO1 is overexpressed in GC and that its overexpression correlates with poor prognosis, as it promotes gastric cancer cell viability.

  10. Down-regulation of GNAO1 increases cell proliferation, while suppressing the senescence of hepatocellular carcinoma cells.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1) interaction partners

  1. These results indicated the interaction of GAP-43 (show GAP43 Antibodies) and Galpha(o) could accelerate conversion of depalmitoylated Galpha(o) but not palmitoylated Galpha(o) from oligomers to monomers, so as to increase the GTPgammaS binding activity of Galpha(o).

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1) interaction partners

  1. Data obtained support the hypothesis that GalphaO-mediated signaling within the presympathetic circuits of the rostral ventral lateral medulla contributes to the autonomic control of the heart.

  2. stimulation of GPR17 (show GPR17 Antibodies) by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (show MBP Antibodies) expression levels mainly by triggering the Galphai/o signaling pathway.

  3. Necdin (show NDN Antibodies) is a candidate downstream effector for Galphao.

  4. This heterozygous Gnao1 +/G184S mutation produces early neonatal and adult lethality accompanied by epileptiform discharges.

  5. These results highlight that sensory neurons of the Galphao-expressing vomeronasal subsystem, together with the receptors they express and the molecular cues they detect, control a wide range of fundamental mating and reproductive behaviors in female mice.

  6. Data indicate that rectifying potassium channel (show KCNAB2 Antibodies) Kir2.4 (show KCNJ14 Antibodies) interacts with G-protein subunit Galphao.

  7. Data show that Galphao is an essential requirement for the display of male-male territorial aggression as well as maternal aggression.

  8. Data suggest that the novel R234H mutation imparts oncogenic properties to Galphao by accelerating nucleotide exchange and rendering it constitutively active.

  9. The 2.9 A crystal structure of the enigmatic, neuronal G protein Galpha(o) in the GTP (show AK3 Antibodies) hydrolytic transition state, complexed with RGS16 (show RGS16 Antibodies).

  10. Go alpha subunit (show POLG Antibodies) mainly appears to be bound to the cell membrane and concentrated in the thin finger-like dendrites of rod bipolar cells, as well as in green fluorescent protein-positive cone bipolar cells.

Caenorhabditis elegans (C. elegans) Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1) interaction partners

  1. Following food deprivation G protein alpha(o) is activated via RIC-8 (show RIC8A Antibodies) activation.

  2. findings show that the GoLoco-containing proteins GPR-1 and GPR-2, as well as the Galpha subunits GOA-1 and GPA-16, were essential for generation of proper pulling forces in asymmetric spindle positioning

  3. Data show that the asymmetry of GPR-1/2 (which act with GOA-1 and GPA-16) localization depends on PAR-3 and its downstream intermediate LET-99, as well as on the MES (show MKS1 Antibodies)-1/SRC-1 (show NCOA1 Antibodies) signaling pathway.

  4. Our results suggest that EGL-47 regulates egg laying by activating Galpha(o) in the hermaphrodite (show DSX Antibodies)-specific motor neurons to inhibit their activity.

  5. down-regulation of EGL-30-DAG signaling by GOA-1 underlies olfactory adaptation and plasticity of chemotaxis

  6. The stravation response is fully dependent on the subsequent activation of the G alpha(q) ortholog EGL-30.

  7. These results suggest that Galpha signaling and LET-99 control centration by regulating polarized actomyosin contraction.

  8. Serotonin signaling is regulated by modulating serotonin biosynthesis and Galphao and Galphaq (show GNAQ Antibodies) act in the same neurons to have opposing effects on behavior, in part, by antagonistically regulating transcription of specific genes.

  9. Goa-1 Goalpha and let-60 Ras act in parallel to gpc-1 in olfactory pathways.

GNAO1 Antigen Profile

Antigen Summary

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.

Alternative names and synonyms associated with GNAO1

  • G protein alpha subunit (gna0) antibody
  • guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1) antibody
  • guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (Gnao1) antibody
  • guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (gnao1) antibody
  • guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a (gnao1a) antibody
  • guanine nucleotide binding protein, alpha O (Gnao1) antibody
  • Protein GOA-1 (goa-1) antibody
  • alphaO antibody
  • AW050213 antibody
  • G-ALPHA-o antibody
  • Galphao antibody
  • Gnao antibody
  • gnao1 antibody
  • gnao1-A antibody
  • RATBPGTPC antibody
  • wu:fq26h05 antibody
  • XGalpha01 antibody
  • zgc:73315 antibody

Protein level used designations for GNAO1

guanine nucleotide-binding protein G(o) subunit alpha , GTP-binding protein alpha o , guanine nucleotide binding protein, alpha O polypeptide 1 , GTP-binding protein G39 , Galpha o1 , GTP-binding protein alpha-o subunit , Go alpha

GENE ID SPECIES
397896 Xenopus laevis
2775 Homo sapiens
50664 Rattus norvegicus
394423 Xenopus laevis
415698 Gallus gallus
609157 Canis lupus familiaris
281792 Bos taurus
100716648 Cavia porcellus
393760 Danio rerio
14681 Mus musculus
172505 Caenorhabditis elegans
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