This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
Hauptmann, Metzger, Schnitzbauer, Cuilleron, Mappus, Luppa: "Syntheses and ligand-binding studies of 1 alpha- and 17 alpha-aminoalkyl dihydrotestosterone derivatives to human sex hormone-binding globulin." in: Steroids, Vol. 68, Issue 7-8, pp. 629-39, (2003) (PubMed).
Aliases for SHBG Proteins
sex hormone binding globulin (SHBG) Proteins sex hormone binding globulin (Shbg) Proteins sex hormone-binding globulin (shbg) Proteins sex hormone binding globulin L homeolog (shbg.L) Proteins ABP Proteins Abpa Proteins SBP Proteins shbg Proteins shbgl Proteins TEBG Proteins wu:fb66h07 Proteins wu:fd55b08 Proteins zgc:123063 Proteins