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anti-Mouse (Murine) IFNAR1 antibody for ELISA

Recommended IFNAR1 Antibody (supplied by: Log in to see )

Antigen
Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies
  • AVP
  • CD118
  • Ifar
  • IFN-alpha-REC
  • IFN-R-1
  • IFNAR
  • Ifnar
  • ifnar1
  • IFNAR1
  • IFNBR
  • IFRC
  • Ifrc
  • Infar
Epitope
AA 1-429
23
17
13
13
11
10
9
9
8
8
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
136
37
20
2
2
2
1
1
Host
Rabbit
107
33
22
Clonality
Polyclonal
Conjugate
This IFNAR1 antibody is un-conjugated
13
11
10
8
6
4
2
2
2
2
2
2
2
2
2
Minimum Detection Limit
0.00975 ng/well
Application
ELISA, Western Blotting (WB)
92
67
38
36
22
10
7
5
4
2
1
1
Supplier
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Catalog No. ABIN2000997
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012092679 ABIN2000995 ELISA Rabbit IgG AA 1-429 Log in to see 114 2
0.0012092679 ABIN2000999 ELISA WB Rabbit IgG AA 1-429 Log in to see Polyclonal 2
0.0012092679 ABIN1582221 IHC ELISA WB Rabbit pSer535, pSer539 Log in to see Polyclonal
0.0012092679 ABIN2622352 ELISA WB Biotin Rabbit IgG AA 104-341 Log in to see Polyclonal
0.0012092679 ABIN2622351 ELISA Rabbit IgG AA 104-341 Log in to see Polyclonal

Top referenced anti-IFNAR1 antibody for ELISA

Similar anti-IFNAR1 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 6 Antibodies
ELISA (Detection) 4 Antibodies
Flow Cytometry (FACS) 10 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies
Epitope AA 1-429
(23), (17), (13), (13), (11), (10), (9), (9), (8), (8), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(136), (37), (20), (2), (2), (2), (1), (1)
Host Rabbit
(107), (33), (22)
Clonality
Polyclonal
Conjugate This IFNAR1 antibody is un-conjugated
(13), (11), (10), (8), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Minimum Detection Limit 0.00975 ng/well
Application ELISA, Western Blotting (WB)
(92), (67), (38), (36), (22), (10), (7), (5), (4), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-IFNAR1 Antibody

Target Details IFNAR1 Application Details Handling References for anti-IFNAR1 Antibody (ABIN2000997) Images
Specificity Mouse IFNAR-1 / CRF2-1
Characteristics Produced in rabbits immunized with purified, recombinant Mouse IFNAR-1 / CRF2-1 (rM IFNAR-1, NP_034638.2, Met 1-Thr 429). Total IgG was purified by Protein A affinity chromatography .
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details IFNAR1

Product Details anti-IFNAR1 Antibody Application Details Handling References for anti-IFNAR1 Antibody (ABIN2000997) Images back to top
Antigen
Alternative Name IFNAR1 (IFNAR1 Antibody Abstract)
Background Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors.
NCBI Accession NP_034638.2
Research Area Chromatin and Nuclear Signaling, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Handling References for anti-IFNAR1 Antibody (ABIN2000997) Images back to top
Application Notes ELISA ELISA: 0.5-1 µg/mL This antibody can be used at 0.5-1 µg/mL with the appropriate secondary reagents to detect Mouse IFNAR-1. The detection limit for Mouse IFNAR-1 is approximately 0.00975 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details References for anti-IFNAR1 Antibody (ABIN2000997) Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

References for anti-IFNAR1 Antibody (ABIN2000997)

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling Images back to top
Background publications

Richter, Duménil, Uzé, Fellous, Pellegrini: "Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1." in: The Journal of biological chemistry, Vol. 273, Issue 38, pp. 24723-9, 1998

Abramovich, Yakobson, Chebath, Revel: "A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor." in: The EMBO journal, Vol. 16, Issue 2, pp. 260-6, 1997

Images

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling References for anti-IFNAR1 Antibody (ABIN2000997) back to top
Supplier Images
Western Blotting (WB) image for anti-IFNAR1 antibody (Interferon (Alpha, beta and Omega) Receptor 1) (AA 1-429) (ABIN2000997) anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) (AA 1-429) antibody