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|Application / Reactivity||Mouse (Murine)||Human|
|Cell Culture (CC)||1 Antibodies||1 Antibodies|
|ELISA||8 Antibodies||59 Antibodies|
|ELISA (Detection)||4 Antibodies||1 Antibodies|
|Flow Cytometry (FACS)||12 Antibodies||41 Antibodies|
|Immunofluorescence (IF)||2 Antibodies||4 Antibodies|
|Immunofluorescence (fixed cells) (IF/ICC)||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||13 Antibodies|
|Immunohistochemistry (IHC)||9 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||4 Antibodies|
|Immunoprecipitation (IP)||3 Antibodies|
|Western Blotting (WB)||16 Antibodies|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|Antigen||Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This IFNAR1 antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-IFNAR1 AntibodyTarget Details IFNAR1 Application Details Handling Images
|Specificity||This antibody detects endogenous levels of IFN-α/βRα protein. (region surrounding Leu461)|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purification||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen|
|Purity||> 95 % pure by SDS-PAGE|
Target Details IFNAR1Product Details anti-IFNAR1 Antibody Application Details Handling Images back to top
|Alternative Name||IFNAR1 (IFNAR1 Antibody Abstract)|
|Background||The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α/βR is expressed as two alternatively spliced transcripts, designated IFN-α/βRα (IFN-α/βR1) and IFN-α/βRβ (IFN- α/βR2), both of which are involved in signal transduction and ligand binding.Synonyms: CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, IFN-R-1, IFN-alpha Receptor alpha, IFN-alpha/beta receptor 1, Interferon-alpha/beta receptor alpha chain, Type I interferon receptor 1|
|Research Area||Chromatin and Nuclear Signaling, Innate Immunity, Cytokines|
|Pathways||JAK-STAT Signaling, Hepatitis C|
Application DetailsProduct Details anti-IFNAR1 Antibody Target Details IFNAR1 Handling Images back to top
ELISA: 1: 20000approx. 1: 40000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||DO NOT FREEZE!|
|Storage Comment||Store the antibody undiluted at 2-8 °C.|
ImagesProduct Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling back to top