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anti-Cow (Bovine) IL-13 antibody for Western Blotting

Recommended IL-13 Antibody (supplied by: Log in to see )

Antigen
Interleukin 13 (IL13) Antibodies
  • IL13
  • IL-13
  • P600
  • Il-13
  • L13
  • interleukin 13
  • interleukin-13
  • IL13
  • Il13
  • IL-13
Reactivity
Pig (Porcine), Sheep (Ovine), Cow (Bovine)
246
78
52
6
6
4
3
2
1
1
1
Host
Rabbit
152
129
69
5
1
Clonality
Polyclonal
Conjugate
This IL-13 antibody is un-conjugated
35
14
13
8
8
7
7
6
6
5
5
5
4
4
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
199
195
103
54
42
26
22
13
12
12
11
10
7
5
4
4
3
3
2
2
1
1
1
1
1
1
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Catalog No. ABIN964711
$ 379.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0923712 ABIN964712 ELISA WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN4324497 ELISA WB Rabbit Log in to see Polyclonal
1 ABIN1102452 ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1585819 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1868576 ICC IHC IP WB Rabbit IgG AA 21-132 Log in to see Polyclonal
1 ABIN2935364 ELISA IF/ICC IHC WB Rabbit AA 21-132 Log in to see Polyclonal

Similar anti-IL-13 Antibodies

Application / Reactivity Cow (Bovine) Pig (Porcine) Sheep (Ovine)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Western Blotting (WB) 7 Antibodies 5 Antibodies 7 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 3 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
ELISA 6 Antibodies 5 Antibodies 6 Antibodies

General

Antigen Interleukin 13 (IL13) Antibodies
Reactivity Pig (Porcine), Sheep (Ovine), Cow (Bovine)
(246), (78), (52), (6), (6), (4), (3), (2), (1), (1), (1)
Host Rabbit
(152), (129), (69), (5), (1)
Clonality
Polyclonal
Conjugate This IL-13 antibody is un-conjugated
(35), (14), (13), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(199), (195), (103), (54), (42), (26), (22), (13), (12), (12), (11), (10), (7), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-IL-13 Antibody

Target Details IL-13 Application Details Handling Images
Specificity This product was Protein-A purified from monospecific antiserum by chromatography. This antibody is specific for swine IL-13 protein. A BLAST analysis was used to suggest reactivity with IL-13 from swine sources based on 100% homology with the immunizing sequence. The following homologies may indicate chances of cross-reactivity when amino acid similarity and not just exact sequence is accounted: 89-90% homology to IL-13 from sheep, dolphin, beluga, and bovine, 83-88% to human and certain monkey IL-13, 80-82% to dusky titi, macaque, baboon, mangabey, dog, llama, camel, and galago, 75-78% to horse, and 67-72% to rat, mouse, and gerbil. Cross-reactivity with IL-13 from other sources has not been determined.
Cross-Reactivity Sheep (Ovine)
Characteristics Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ralpha) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. Anti-IL-13 antibody antibody is ideal for investigators involved in Cancer and Immunology research.
Purification purified
Sterility Sterile filtered
Immunogen This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant protein raised in yeast, corresponding to mature swine IL-13 protein.
Immunogen Type: RecombinantProtein
Isotype IgG

Target Details IL-13

Product Details anti-IL-13 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL13 (IL13 Antibody Abstract)
Background Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. Anti-IL-13 antibody antibody is ideal for investigators involved in Cancer and Immunology research.
Synonyms: Interleukin-13, IL-13
Gene ID 396721, 189176151
UniProt B3GDZ5
Research Area Cancer, Cytokines, Innate Immunity
Pathways JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport

Application Details

Product Details anti-IL-13 Antibody Target Details IL-13 Handling Images back to top
Application Notes IL-13 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 13.2 kDa in size corresponding to swine IL-13 protein by western blotting in the appropriate cell lysate or extract.
Comment

Gene Name: IL-13

Restrictions For Research Use only

Handling

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details Images back to top
Format Lyophilized
Reconstitution Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
Concentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Expiry Date 12 months

Images

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-IL-13 antibody (Interleukin 13) (ABIN964711) Western blot using protein-A purified anti-swine IL-13 antibody shows detection of re...