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|Antigen||Interleukin 15 (IL15) Antibodies|
|Epitope||AA 49-162 Alternatives|
|Conjugate||This IL15 antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
|6 references available|
|Supplier||Log in to see|
Product Details anti-IL15 AntibodyTarget Details IL15 Application Details Handling References for anti-IL15 antibody (ABIN4900390) Images
|Specificity||Detects human IL-15 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2, recombinant mouse IL-15, or rhIL-21 is observed.|
|Purification||Protein A or G purified from ascites|
|Sterility||0.2 μm filtered|
|Endotoxin Level||<0.10 EU per 1 μg of the antibody by the LAL method.|
|Immunogen||E. coli-derived recombinant human IL-15, Asn49-Ser162, Accession # P40933|
Target Details IL15Product Details anti-IL15 Antibody Application Details Handling References for anti-IL15 antibody (ABIN4900390) Images back to top
|Alternative Name||IL-15 (IL15 Antibody Abstract)|
|Background||Alternative Names: IL15, IL-15MGC9721, interleukin 15, interleukin-15|
|Research Area||Immunology, Cytokines, Innate Immunity|
|Pathways||JAK-STAT Signaling, Glycosaminoglycan Metabolic Process|
Application DetailsProduct Details anti-IL15 Antibody Target Details IL15 Handling References for anti-IL15 antibody (ABIN4900390) Images back to top
Western Blot 1 μg/mL
Neutralization 0.1-0.5 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL15 Antibody Target Details IL15 Application Details References for anti-IL15 antibody (ABIN4900390) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-IL15 antibody (ABIN4900390)Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling Images back to top
|Product cited in:||
Ciccocioppo, Gallia, Avanzini, Betti, Picone, Vanoli, Paganini, Biagi, Maccario, Corazza: "A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions." in: Mayo Clinic proceedings, Vol. 91, Issue 6, pp. 812-9, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Anguille, Van Acker, Van den Bergh, Willemen, Goossens, Van Tendeloo, Smits, Berneman, Lion: "Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner." in: PLoS ONE, Vol. 10, Issue 5, pp. e0123340, 2015 Method employed by authors: Neutralization (Neut) (Sample species: Human).
Marra, Mathew, Grigoriadis, Wu, Kyle-Cezar, Watkins, Rashid, De Rinaldis, Hessey, Gazinska, Hayday, Tutt: "IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers." in: Cancer research, Vol. 74, Issue 17, pp. 4908-21, 2014 Method employed by authors: Blocking Peptide (BP) (Sample species: Human).
Muntasell, Magri, Pende, Angulo, López-Botet: "Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection." in: Blood, Vol. 115, Issue 25, pp. 5170-9, 2010 Method employed by authors: Neutralization (Neut) (Sample species: Human).
Tsukamoto, Huang, Dorsey, Carns, Sharma: "Juxtacrine function of interleukin-15/interleukin-15 receptor system in tumour derived human B-cell lines." in: Clinical and experimental immunology, Vol. 146, Issue 3, pp. 559-66, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Ong, Hamid, Travers, Strickland, Al Kerithy, Boguniewicz, Leung: "Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 1, pp. 505-10, 2001 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
ImagesProduct Details anti-IL15 Antibody Target Details IL15 Application Details Handling References for anti-IL15 antibody (ABIN4900390) back to top