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anti-Human IL15 antibody for Neutralization

Recommended IL15 Antibody (supplied by: Log in to see )

Antigen
Interleukin 15 (IL15) Antibodies
  • IL15
  • AI503618
  • IL-15
  • interleukin 15
  • IL15
  • Il15
Epitope
AA 49-162
63
12
11
7
6
5
5
5
4
4
1
1
1
1
1
1
1
Reactivity
Human
206
47
24
8
8
6
5
2
2
1
1
1
Host
Mouse
132
109
14
5
5
4
Clonality
Monoclonal
Conjugate
This IL15 antibody is un-conjugated
32
15
9
7
5
5
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
179
172
59
31
29
25
24
10
10
8
7
7
5
4
3
2
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN4900390
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
38.684093 ABIN4900389 FACS Neut WB Mouse IgG1 AA 49-162 Log in to see 34559 6
1 ABIN464933 ELISA IHC (p) Neut WB Biotin Rabbit Log in to see Polyclonal
1 ABIN464930 ELISA IHC (p) Neut WB Rabbit Log in to see Polyclonal
1 ABIN4324539 BP Neut WB Mouse IgG1 Log in to see MM0368-13S34
1 ABIN208838 IP Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1983256 Neut WB Mouse IgG1 AA 49-162 Log in to see MM0368-13S34
1 ABIN1967974 IHC (p) Neut Rat IgG2a Log in to see AIO-3
1 ABIN2287805 Neut ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Log in to see Polyclonal
1 ABIN2287808 Neut ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN2287807 Neut ELISA WB APC Rabbit IgG Log in to see Polyclonal
1 ABIN2287812 Neut ELISA WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN2287814 Neut ELISA WB PE Rabbit IgG Log in to see Polyclonal
1 ABIN2287810 Neut ELISA WB FITC Rabbit IgG Log in to see Polyclonal
1 ABIN2287803 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2287774 IP Neut ELISA WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-IL15 antibody for Neutralization

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General

Antigen Interleukin 15 (IL15) Antibodies
Epitope AA 49-162
(63), (12), (11), (7), (6), (5), (5), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(206), (47), (24), (8), (8), (6), (5), (2), (2), (1), (1), (1)
Host Mouse
(132), (109), (14), (5), (5), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL15 antibody is un-conjugated
(32), (15), (9), (7), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
(179), (172), (59), (31), (29), (25), (24), (10), (10), (8), (7), (7), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-IL15 Antibody

Target Details IL15 Application Details Handling References for anti-IL15 Antibody (ABIN4900390) Images
Specificity Detects human IL-15 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2, recombinant mouse IL-15, or rhIL-21 is observed.
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen E. coli-derived recombinant human IL-15, Asn49-Ser162, Accession # P40933
Clone 34559
Isotype IgG1

Target Details IL15

Product Details anti-IL15 Antibody Application Details Handling References for anti-IL15 Antibody (ABIN4900390) Images back to top
Antigen
Alternative Name IL-15 (IL15 Antibody Abstract)
Background Alternative Names: IL15, IL-15MGC9721, interleukin 15, interleukin-15
Gene ID 3600
UniProt P40933
Research Area Immunology, Cytokines, Innate Immunity
Pathways JAK-STAT Signaling, Glycosaminoglycan Metabolic Process

Application Details

Product Details anti-IL15 Antibody Target Details IL15 Handling References for anti-IL15 Antibody (ABIN4900390) Images back to top
Application Notes Western Blot 1 μg/mL
Neutralization 0.1-0.5 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL15 Antibody Target Details IL15 Application Details References for anti-IL15 Antibody (ABIN4900390) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL15 Antibody (ABIN4900390)

Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling Images back to top
Product cited in:

Ciccocioppo, Gallia, Avanzini, Betti, Picone, Vanoli, Paganini, Biagi, Maccario, Corazza: "A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions." in: Mayo Clinic proceedings, Vol. 91, Issue 6, pp. 812-9, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Anguille, Van Acker, Van den Bergh, Willemen, Goossens, Van Tendeloo, Smits, Berneman, Lion: "Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner." in: PLoS ONE, Vol. 10, Issue 5, pp. e0123340, 2015 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Marra, Mathew, Grigoriadis, Wu, Kyle-Cezar, Watkins, Rashid, De Rinaldis, Hessey, Gazinska, Hayday, Tutt: "IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers." in: Cancer research, Vol. 74, Issue 17, pp. 4908-21, 2014 Method employed by authors: Blocking Peptide (BP) (Sample species: Human).

Muntasell, Magri, Pende, Angulo, López-Botet: "Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection." in: Blood, Vol. 115, Issue 25, pp. 5170-9, 2010 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Tsukamoto, Huang, Dorsey, Carns, Sharma: "Juxtacrine function of interleukin-15/interleukin-15 receptor system in tumour derived human B-cell lines." in: Clinical and experimental immunology, Vol. 146, Issue 3, pp. 559-66, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ong, Hamid, Travers, Strickland, Al Kerithy, Boguniewicz, Leung: "Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 1, pp. 505-10, 2001 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Images

Product Details anti-IL15 Antibody Target Details IL15 Application Details Handling References for anti-IL15 Antibody (ABIN4900390) back to top
Supplier Images
Neutralization (Neut) image for anti-IL15 antibody (Interleukin 15) (AA 49-162) (ABIN4900390) Cell Proliferation Induced by IL-15 and Neutralization by Human IL-15 Antibody. Recom...