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|Antigen||Interleukin 15 Receptor, alpha (IL15RA) Antibodies|
|Epitope||AA 31-174 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This IL15RA antibody is un-conjugated Alternatives|
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-IL15RA AntibodyTarget Details IL15RA Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for IL15RA detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for IL15RA detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
Gene Name: interleukin 15 receptor subunit alpha
Protein Name: Interleukin-15 receptor subunit alpha
|Purification||Immunogen affinity purified.|
|Immunogen||E. coli-derived human IL15RA recombinant protein (Position: I31-T174).|
Target Details IL15RAProduct Details anti-IL15RA Antibody Application Details Handling Images back to top
|Alternative Name||IL15RA (IL15RA Antibody Abstract)|
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Synonyms: Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD215, Soluble interleukin-15 receptor subunit alpha, sIL-15 receptor subunit alpha, sIL-15R-alpha, sIL-15RA, IL15RA
|Research Area||Signaling, Apoptosis/Necrosis|
Application DetailsProduct Details anti-IL15RA Antibody Target Details IL15RA Handling Images back to top
|Application Notes||Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.|
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL15RA Antibody Target Details IL15RA Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.