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anti-Human IL2 antibody for Neutralization

Recommended IL2 Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 (IL2) Antibodies
  • Il-2
  • IL-2
  • IL2
  • il2
  • lymphokine
  • POIL2
  • TCGF
Reactivity
Human
471
258
89
20
18
7
6
4
4
3
2
2
1
1
Host
Rat
297
260
243
17
7
4
Clonality
Monoclonal
Conjugate
This IL2 antibody is un-conjugated
95
51
50
28
21
16
15
12
12
9
7
7
7
7
7
7
7
7
6
6
6
6
5
5
4
4
4
4
4
2
2
2
2
2
1
1
1
1
Application
Intracellular Staining (ICS), Neutralization (Neut), ELISA
469
384
219
69
65
55
46
43
38
36
30
27
19
15
13
9
7
6
6
4
4
4
3
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1176901
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087393454 ABIN964758 IHC Neut RIA ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087393454 ABIN1102473 IHC (p) Neut ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087393454 ABIN1102474 IHC (p) Neut ELISA WB Goat Log in to see Polyclonal
0.00087393454 ABIN218079 IHC (fro) Neut WB Mouse IgG2a, kappa Log in to see
0.00087393454 ABIN242200 Neut WB Rabbit Log in to see Polyclonal
0.00087393454 ABIN603354 IP Neut RIA WB Rabbit IgG Log in to see Polyclonal
0.00087393454 ABIN1983278 Neut IHC Mouse IgG1 AA 21-153 Log in to see MM0390-1V26
0.00087393454 ABIN3198814 Neut ELISA Mouse IgG1 Log in to see B025M
0.00087393454 ABIN2288312 DB Neut IHC Mouse IgG2a kappa Log in to see 2B2-121
0.00087393454 ABIN2680387 Func Neut Mouse IgG2a kappa Log in to see AB12-3G4
0.00087393454 ABIN2487783 IP Neut IHC ELISA WB Mouse IgG2a Log in to see YNRhIL2-
0.00087393454 ABIN4324781 BP IHC IHC (fro) Neut WB Mouse IgG1 Log in to see MM0390-1V26
0.00087393454 ABIN307061 Neut Mouse IgG2a Log in to see 297C16F11 1
0.00087393454 ABIN2288429 Neut Mouse IgG1 Log in to see 6D492
0.00087393454 ABIN2288453 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087393454 ABIN1002609 Neut Mouse IgG1 Log in to see
0.00087393454 ABIN2144099 Neut WB Rabbit IgG Log in to see Polyclonal
0.00087393454 ABIN2288386 Neut ELISA WB Alkaline Phosphatase (AP) Rabbit Log in to see Polyclonal
0.00087393454 ABIN2288389 Neut ELISA WB Biotin Rabbit Log in to see Polyclonal
0.00087393454 ABIN2288391 Neut ELISA WB FITC Rabbit Log in to see Polyclonal

Top referenced anti-IL2 antibody for Neutralization

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General

Antigen Interleukin 2 (IL2) Antibodies
Reactivity Human
(471), (258), (89), (20), (18), (7), (6), (4), (4), (3), (2), (2), (1), (1)
Host Rat
(297), (260), (243), (17), (7), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 antibody is un-conjugated
(95), (51), (50), (28), (21), (16), (15), (12), (12), (9), (7), (7), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Intracellular Staining (ICS), Neutralization (Neut), ELISA
(469), (384), (219), (69), (65), (55), (46), (43), (38), (36), (30), (27), (19), (15), (13), (9), (7), (6), (6), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL2 Antibody

Target Details IL2 Application Details Handling References for anti-IL2 Antibody (ABIN1176901) Images
Brand BD Pharmingen™
Characteristics Neutralization Activity: This antibody has been reported to be useful for the neutralization of recombinant human IL-2. Neutralization activity may be measured with a proliferation assay using 100 pg/mL recombinant human IL-2 (Cat. No. 554603) to stimulate CTLL-2 cells at 2x10^4 cells/mL as indicator cells (i.e. preincubation of the antibody with recombinant human IL-2 for 60 minutes).
50% Neutralization (ND50) at 0.1-1.5 µg/mL
>95% Neutralization at 3 - 15 myg/mL
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen Human IL-2 Recombinant Protein
Clone MQ1-17H12
Isotype IgG2a, kappa

Target Details IL2

Product Details anti-IL2 Antibody Application Details Handling References for anti-IL2 Antibody (ABIN1176901) Images back to top
Antigen
Alternative Name IL-2 (IL2 Antibody Abstract)
Background The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2). The immunogen used to generate the MQ1-17H12 hybridoma was recombinant human IL-2. Unconjugated or purified forms of this antibody have been reported to be neutralizing for human IL-2 bioactivity.
Research Area Cancer
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL2 Antibody Target Details IL2 Handling References for anti-IL2 Antibody (ABIN1176901) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-IL2 Antibody Target Details IL2 Application Details References for anti-IL2 Antibody (ABIN1176901) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative Azide free
Storage 4 °C
Storage Comment Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-IL2 Antibody (ABIN1176901)

Product Details anti-IL2 Antibody Target Details IL2 Application Details Handling Images back to top
Product cited in:

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996

Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." in: Immunology, Vol. 83, Issue 1, pp. 16-24, 1995

Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." in: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, 1994

Gillis, Ferm, Ou, Smith: "T cell growth factor: parameters of production and a quantitative microassay for activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 120, Issue 6, pp. 2027-32, 1978