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anti-Human IL2 antibody for Neutralization

Recommended IL2 Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 (IL2) Antibodies
  • IL2
  • IL-2
  • il2
  • TCGF
  • lymphokine
  • Il-2
  • POIL2
  • interleukin 2
  • IL2
  • il2
  • Il2
Epitope
AA 21-153
26
20
18
17
15
15
11
10
10
8
4
4
3
3
2
2
2
2
2
1
1
1
1
Reactivity
Human
470
257
100
24
18
7
6
6
4
4
3
2
1
1
Host
Mouse
304
267
228
17
7
4
Clonality
Monoclonal
Conjugate
This IL2 antibody is un-conjugated
92
51
51
27
19
15
15
12
12
9
8
7
7
7
7
7
7
6
6
6
6
5
5
4
4
4
4
4
4
4
3
3
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
469
402
210
89
72
50
49
47
38
34
26
23
15
10
8
7
7
6
4
4
3
3
2
2
2
1
1
1
1
1
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Catalog No. ABIN4899553
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
38.57912 ABIN4899552 FACS ICC Neut Mouse IgG1 AA 21-153 Log in to see 5334 9
1 ABIN1176901 ICS Neut ELISA Rat IgG2a, kappa Log in to see MQ1-17H12 4
1 ABIN964758 IHC Neut RIA ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1102473 IHC (p) Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN411517 Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN1102474 IHC (p) Neut ELISA WB Goat Log in to see Polyclonal
1 ABIN4324781 BP IHC IHC (fro) Neut WB Mouse IgG1 Log in to see MM0390-1V26
1 ABIN1983278 Neut IHC Mouse IgG1 AA 21-153 Log in to see MM0390-1V26
1 ABIN3198814 Neut ELISA Mouse IgG1 Log in to see B025M
1 ABIN4965361 Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN218079 IHC (fro) Neut WB Mouse IgG2a, kappa Log in to see
1 ABIN603354 IP Neut RIA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2487783 IP Neut IHC ELISA WB Mouse IgG2a Log in to see YNRhIL2-
1 ABIN2288312 DB Neut IHC Mouse IgG2a kappa Log in to see 2B2-121
1 ABIN242200 Neut WB Rabbit Log in to see Polyclonal
1 ABIN307061 Neut Mouse IgG2a Log in to see 297C16F11 1
1 ABIN2288429 Neut Mouse IgG1 Log in to see 6D492
1 ABIN2288453 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2748971 ELISpot FACS Neut ELISA WB Mouse IgG1 Log in to see B-G5
1 ABIN1002609 Neut Mouse IgG1 Log in to see

Top referenced anti-IL2 antibody for Neutralization

Similar anti-IL2 Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 8 Antibodies
Blocking Peptide (BP) 2 Antibodies
Dot Blot (DB) 4 Antibodies
ELISA 266 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot 5 Antibodies
Enzyme Immunoassay (EIA) 24 Antibodies
Flow Cytometry (FACS) 108 Antibodies
Functional Studies (Func) 16 Antibodies
Immunoassay (IA) 3 Antibodies
Immunocytochemistry (ICC) 26 Antibodies
Immunofluorescence (IF) 17 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 61 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies

General

Antigen Interleukin 2 (IL2) Antibodies
Epitope AA 21-153
(26), (20), (18), (17), (15), (15), (11), (10), (10), (8), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(470), (257), (100), (24), (18), (7), (6), (6), (4), (4), (3), (2), (1), (1)
Host Mouse
(304), (267), (228), (17), (7), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 antibody is un-conjugated
(92), (51), (51), (27), (19), (15), (15), (12), (12), (9), (8), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
(469), (402), (210), (89), (72), (50), (49), (47), (38), (34), (26), (23), (15), (10), (8), (7), (7), (6), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-IL2 Antibody

Target Details IL2 Application Details Handling References for anti-IL2 Antibody (ABIN4899553) Images
Specificity Detects human IL-2 in direct ELISAs. Does not cross-react with recombinant IL-2 from mouse, rat, pig, or cotton rat.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen E. coli-derived recombinant human IL-2, Ala21-Thr153, Accession # NP_000577
Clone 5334
Isotype IgG1

Target Details IL2

Product Details anti-IL2 Antibody Application Details Handling References for anti-IL2 Antibody (ABIN4899553) Images back to top
Antigen
Alternative Name IL-2 (IL2 Antibody Abstract)
Gene ID 3558
NCBI Accession NP_000577
Research Area Virology, Immunology, Cytokines, Cancer, Inflammation
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity

Application Details

Product Details anti-IL2 Antibody Target Details IL2 Handling References for anti-IL2 Antibody (ABIN4899553) Images back to top
Application Notes Neutralization 0.015-0.03 μg/mL, Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells, Immunocytochemistry 8-25 μg/mL, CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL2 Antibody Target Details IL2 Application Details References for anti-IL2 Antibody (ABIN4899553) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C/-20 °C/-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL2 Antibody (ABIN4899553)

Product Details anti-IL2 Antibody Target Details IL2 Application Details Handling Images back to top
Product cited in:

Locci, Wu, Arumemi, Mikulski, Dahlberg, Miller, Crotty: "Activin A programs the differentiation of human TFH cells." in: Nature immunology, Vol. 17, Issue 8, pp. 976-84, 2016 Method employed by authors: Biochemical Assay (BCA) (Sample species: Human).

Jiang, Chen, An, Yang, Zhang, Cheng: "Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling." in: Scientific reports, Vol. 6, pp. 32320, 2016 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Nata, Basheer, Cocchi, van Besien, Massoud, Jacobson, Azimi, Tagaya: "Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum." in: The Journal of biological chemistry, Vol. 290, Issue 37, pp. 22338-51, 2015 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Weissmüller, Semmler, Kalinke, Christians, Müller-Berghaus, Waibler: "ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation." in: Blood, Vol. 119, Issue 26, pp. 6268-77, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Hutnick, Carnathan, Demers, Makedonas, Ertl, Betts: "Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive." in: Vaccine, Vol. 28, Issue 8, pp. 1932-41, 2010 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Withers, Fiorini, Fischer, Ettinger, Lipsky, Grammer: "T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue." in: Blood, Vol. 109, Issue 11, pp. 4856-64, 2007 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Karenko, Hahtola, Päivinen, Karhu, Syrjä, Kähkönen, Nedoszytko, Kytölä, Zhou, Blazevic, Pesonen, Nevala, Nupponen, Sihto, Krebs, Poustka, Roszkiewicz, Saksela, Peterson, Visakorpi, Ranki: "Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue." in: Cancer research, Vol. 65, Issue 18, pp. 8101-10, 2005 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Sen, Chunsong, Baojun, Linjie, Qun, San, Qiuping, Junyan, Zhang, Jinquan: "Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells." in: Immunology, Vol. 112, Issue 2, pp. 274-89, 2004 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Herrero, Hu, Li, Samuels, Sharif, Kotenko, Ivashkiv: "Reprogramming of IL-10 activity and signaling by IFN-gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 10, pp. 5034-41, 2003 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Images

Product Details anti-IL2 Antibody Target Details IL2 Application Details Handling References for anti-IL2 Antibody (ABIN4899553) back to top
Supplier Images
Neutralization (Neut) image for anti-IL2 antibody (Interleukin 2) (AA 21-153) (ABIN4899553) Cell Proliferation Induced by IL-2 and Neutralization by Human IL-2 Antibody. Recombi...
Immunocytochemistry (ICC) image for anti-IL2 antibody (Interleukin 2) (AA 21-153) (ABIN4899553) IL-2 in Human PBMCs. IL-2 was detected in immersion fixed human peripheral blood mono...