anti-Human IL21 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL21 Antibody (supplied by: Log in to see )

Antigen
Interleukin 21 (IL21) Antibodies
  • IL-21
  • Za11
  • interleukin 21
  • interleukin 21-like
  • IL21
  • Il21
  • LOC100344172
Epitope
Center
23
18
15
13
8
8
6
6
6
5
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
203
102
23
10
5
5
4
1
1
Host
Rabbit
165
70
41
11
5
Clonality
Polyclonal
Conjugate
This IL21 antibody is un-conjugated
20
15
11
10
9
8
6
6
5
5
5
5
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
186
133
49
38
33
25
14
13
7
6
4
4
4
4
3
2
2
1
1
Supplier
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Catalog No. ABIN315232
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN748133 IF (p) IHC (p) Rabbit IgG AA 110-145 Log in to see Polyclonal 1
1 ABIN2474979 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 1
1 ABIN213939 IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN449981 IHC (p) IHC ELISA Goat N-Term Log in to see Polyclonal
1 ABIN748142 IHC (p) HRP Rabbit IgG AA 110-145 Log in to see Polyclonal
1 ABIN748135 IHC (p) Biotin Rabbit IgG AA 110-145 Log in to see Polyclonal
1 ABIN1735877 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1868629 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN5551440 IHC (p) WB Rabbit Center Log in to see Polyclonal
1 ABIN4995104 IHC IHC (fro) IHC (p) FITC Mouse IgG1 kappa Log in to see 14k5A9
1 ABIN1812111 FACS IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN2474976 ELISA ICC IHC (p) Goat IgG N-Term Log in to see Polyclonal
1 ABIN2768629 IHC (p) WB Rabbit Internal Region Log in to see Polyclonal

General

Antigen Interleukin 21 (IL21) Antibodies
Epitope Center
(23), (18), (15), (13), (8), (8), (6), (6), (6), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(203), (102), (23), (10), (5), (5), (4), (1), (1)
Host Rabbit
(165), (70), (41), (11), (5)
Clonality
Polyclonal
Conjugate This IL21 antibody is un-conjugated
(20), (15), (11), (10), (9), (8), (6), (6), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(186), (133), (49), (38), (33), (25), (14), (13), (7), (6), (4), (4), (4), (4), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-IL21 Antibody

Target Details IL21 Application Details Handling ProductDetails: References for anti-IL21 antibody (ABIN315232) Images
Specificity Synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor
Purification Immunogen affinity purified
Immunogen A synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor .

Target Details IL21

Product Details anti-IL21 Antibody Application Details Handling ProductDetails: References for anti-IL21 antibody (ABIN315232) Images back to top
Antigen
Alternative Name IL-21 (IL21 Antibody Abstract)
Background Gene Symbol: IL21
Gene ID 59067
UniProt Q9HBE4
Research Area Immunology, Cytokines, Inflammation, Virology, Cancer
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-IL21 Antibody Target Details IL21 Handling ProductDetails: References for anti-IL21 antibody (ABIN315232) Images back to top
Application Notes Western Blot 0.5-1 μg/mL, Immunohistochemistry 5 μg/mL, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 5 μg/mL, Immunohistochemistry-Frozen 1:10-1:500IHC-F usage is reported in scientific literature (PMID: 23607532).
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-IL21 Antibody Target Details IL21 Application Details ProductDetails: References for anti-IL21 antibody (ABIN315232) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ProductDetails: References for anti-IL21 antibody (ABIN315232)

Product Details anti-IL21 Antibody Target Details IL21 Application Details Handling Images back to top
Product cited in:

Verstappen, Kroese, Meiners, Corneth, Huitema, Haacke, van der Vegt, Arends, Vissink, Bootsma, Abdulahad: "B Cell Depletion Therapy Normalizes Circulating Follicular Th Cells in Primary Sjögren Syndrome." in: The Journal of rheumatology, Vol. 44, Issue 1, pp. 49-58, 2017 (Sample species: Human).

Hashimoto-Kataoka, Hosen, Sonobe, Arita, Yasui, Masaki, Minami, Inagaki, Miyagawa, Sawa, Murakami, Kumanogoh, Yamauchi-Takihara, Okumura, Kishimoto, Komuro, Shirai, Sakata, Nakaoka: "Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2677-86, 2015 Further details: Immunohistochemistry (Paraffin-embedded Sections),Immunohistochemistry (Frozen Sections)

Wen, Zeng, Gui, Li, Li: "Changes in the expression of Th17 cell-associated cytokines in the development of rheumatic heart disease." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 24, Issue 6, pp. 382-7, 2015 (Sample species: Rat (Rattus)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Liu, Xia, Wu, Wu, Tang, Chen, Xu, Cong, Xu, Liu: "Anti-tumour necrosis factor therapy enhances mucosal healing through down-regulation of interleukin-21 expression and T helper type 17 cell infiltration in Crohn's disease." in: Clinical and experimental immunology, Vol. 173, Issue 1, pp. 102-11, 2013 (Sample species: Human). Further details: Immunohistochemistry (Frozen Sections)

Hodge, Ziesmer, Yang, Secreto, Gertz, Novak, Ansell: "IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia." in: Blood, Vol. 120, Issue 18, pp. 3774-82, 2012

Images

Product Details anti-IL21 Antibody Target Details IL21 Application Details Handling ProductDetails: References for anti-IL21 antibody (ABIN315232) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 21 (IL21) (Center) antibody (ABIN315232) Western Blot: IL-21 Antibody [NBP1-02706] - Expression in HL-60 cell lysate in the ab...
Immunofluorescence (IF) image for anti-Interleukin 21 (IL21) (Center) antibody (ABIN315232) Immunocytochemistry/Immunofluorescence: IL-21 Antibody [NBP1-02706] - K562 cells.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Interleukin 21 (IL21) (Center) antibody (ABIN315232) Immunohistochemistry-Paraffin: IL-21 Antibody [NBP1-02706] - Staining of human spleen...