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anti-Human IL21 antibody for Western Blotting

Recommended IL21 Antibody (supplied by: Log in to see )

Antigen
Interleukin 21 (IL21) Antibodies
  • IL-21
  • Za11
  • interleukin 21
  • interleukin 21-like
  • IL21
  • Il21
  • LOC100344172
Epitope
AA 104-132, C-Term
23
16
15
13
8
8
6
6
6
6
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
195
92
24
7
5
5
2
1
1
Host
Rabbit
156
66
30
11
5
Clonality
Polyclonal
Conjugate
This IL21 antibody is un-conjugated
17
15
10
9
8
8
6
6
5
5
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
Application
Western Blotting (WB)
175
125
40
39
32
25
14
13
7
6
5
4
4
3
2
2
1
1
1
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Catalog No. ABIN657761
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0923712 ABIN499986 EIA IF WB Rabbit IgG Intermediate Domain Log in to see Polyclonal 1
3.0923712 ABIN315232 ICC IF IHC IHC (fro) IHC (p) WB Rabbit Center Log in to see Polyclonal 5
3.0923712 ABIN4324913 ICC IF IHC WB Mouse IgG1 kappa Log in to see 14k5H3 1
3.0923712 ABIN3185169 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
3.0923712 ABIN3198158 IC IF IHC WB Rabbit Log in to see Polyclonal
3.0923712 ABIN4324904 ELISA ICC IF WB Rabbit all Isoforms Log in to see Polyclonal
3.0923712 ABIN4324915 WB Mouse IgG1 kappa Log in to see 14k5A9
3.0923712 ABIN2468185 ELISA WB Chicken AA 33-111 Log in to see Polyclonal
3.0923712 ABIN2474977 IHC (fro) WB Rabbit IgG Center Log in to see Polyclonal 1
3.0923712 ABIN1174928 ICC IHC IP WB Rabbit IgG AA 23-155 Log in to see Polyclonal
3.0923712 ABIN2563408 IF IHC WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN4225394 WB Mouse Log in to see Polyclonal
3.0923712 ABIN1868629 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN528380 WB Mouse AA 1-162, full length Log in to see Polyclonal
3.0923712 ABIN528381 PLA WB Rabbit AA 1-162, full length Log in to see Polyclonal
3.0923712 ABIN1030836 IHC ELISA WB Rabbit Extracellular Domain Log in to see Polyclonal
3.0923712 ABIN1030955 ICC ELISA WB Rabbit Middle Region Log in to see Polyclonal
3.0923712 ABIN1031410 ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN2788558 WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1452162 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 2

Top referenced anti-IL21 antibody for Western Blotting

  • Human Polyclonal IL21 Primary Antibody for ICC, IF - ABIN315232 (5 Publications): Liu, Xia, Wu, Wu, Tang, Chen, Xu, Cong, Xu, Liu: Anti-tumour necrosis factor therapy enhances mucosal healing through down-regulation of interleukin-21 expression and T helper type 17 cell infiltration in Crohn's disease. in Clinical and experimental immunology 2013 (PubMed)

  • Human Polyclonal IL21 Primary Antibody for ICC, ELISA - ABIN1002621 (3 Publications): Asao, Okuyama, Kumaki, Ishii, Tsuchiya, Foster, Sugamura: Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)

  • Human Polyclonal IL21 Primary Antibody for IHC (p), WB - ABIN2474979 (1 Publications): Tripodo, Gri, Piccaluga, Frossi, Guarnotta, Piconese, Franco, Vetri, Pucillo, Florena, Colombo, Pileri: Mast cells and Th17 cells contribute to the lymphoma-associated pro-inflammatory microenvironment of angioimmunoblastic T-cell lymphoma. in The American journal of pathology 2010 (PubMed)

  • Human Monoclonal IL21 Primary Antibody for ICC, IF - ABIN4324913 (1 Publications): Chen, Xiao, Lao, Wei, Liu, Zeng, Wang, Ouyang, Chen, Chan, Shi, Zheng, Kuang: Polarization of Tissue-Resident TFH-Like Cells in Human Hepatoma Bridges Innate Monocyte Inflammation and M2b Macrophage Polarization. in Cancer discovery 2016 (PubMed)

  • Human Polyclonal IL21 Primary Antibody for ELISA, WB - ABIN1452162 (2 Publications): Parrish-Novak, Dillon, Nelson, Hammond, Sprecher, Gross, Johnston, Madden, Xu, West, Schrader, Burkhead, Heipel, Brandt, Kuijper, Kramer, Conklin, Presnell, Berry, Shiota, Bort, Hambly, Mudri, Clegg et al.: Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. ... in Nature 2000 (PubMed)

Similar anti-IL21 Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 4 Antibodies
ELISA 85 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 10 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 30 Antibodies
Immunofluorescence (IF) 25 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 34 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 1 Antibodies

General

Antigen Interleukin 21 (IL21) Antibodies
Epitope AA 104-132, C-Term
(23), (16), (15), (13), (8), (8), (6), (6), (6), (6), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(195), (92), (24), (7), (5), (5), (2), (1), (1)
Host Rabbit
(156), (66), (30), (11), (5)
Clonality (Clone)
Polyclonal   ( )
Conjugate This IL21 antibody is un-conjugated
(17), (15), (10), (9), (8), (8), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(175), (125), (40), (39), (32), (25), (14), (13), (7), (6), (5), (4), (4), (3), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL21 Antibody

Target Details IL21 Application Details Handling References for anti-IL21 Antibody (ABIN657761) Images
Specificity This IL21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of human IL21.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This IL21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 AA from the C-terminal region of human IL21.
Clone RB33749
Isotype Ig

Target Details IL21

Product Details anti-IL21 Antibody Application Details Handling References for anti-IL21 Antibody (ABIN657761) Images back to top
Antigen
Alternative Name IL21 (IL21 Antibody Abstract)
Background Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B-and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Synonyms: Interleukin-21,IL21,
Molecular Weight 17923 DA
Gene ID 59067
NCBI Accession NP_068575
UniProt Q9HBE4
Research Area Cell Signaling, Protein Modifications, Cell Structure
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-IL21 Antibody Target Details IL21 Handling References for anti-IL21 Antibody (ABIN657761) Images back to top
Application Notes WB = 1:1000
Restrictions For Research Use only

Handling

Product Details anti-IL21 Antibody Target Details IL21 Application Details References for anti-IL21 Antibody (ABIN657761) Images back to top
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment IL21 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months

References for anti-IL21 Antibody (ABIN657761)

Product Details anti-IL21 Antibody Target Details IL21 Application Details Handling Images back to top
Background publications

Petukhova, Duvic, Hordinsky, Norris, Price, Shimomura, Kim, Singh, Lee, Chen, Meyer, Paus, Jahoda, Amos, Gregersen, Christiano: "Genome-wide association study in alopecia areata implicates both innate and adaptive immunity." in: Nature, Vol. 466, Issue 7302, pp. 113-7, 2010

Yue, Lo, Sakhdari, Lee, Kovacs, Benko, Liu, Song, Jones, Sheth, Chege, Kaul, Ostrowski: "HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 498-506, 2010

Pallone, Fina, Caruso, Monteleone: "Role of IL-21 in inflammatory bowel disease." in: Expert review of clinical immunology, Vol. 6, Issue 4, pp. 537-41, 2010

Images

Product Details anti-IL21 Antibody Target Details IL21 Application Details Handling References for anti-IL21 Antibody (ABIN657761) back to top
Supplier Images
Western Blotting (WB) image for anti-IL21 antibody (Interleukin 21) (AA 104-132) (ABIN657761) Western blot analysis of IL21 (arrow) using rabbit polyclonal IL21 Antibody (C-term) ...