Browse our anti-IL21 Receptor (IL21R) Antibodies

Full name:
anti-Interleukin 21 Receptor Antibodies (IL21R)
On are 140 Interleukin 21 Receptor (IL21R) Antibodies from 26 different suppliers available. Additionally we are shipping IL21 Receptor Proteins (24) and IL21 Receptor Kits (10) and many more products for this protein. A total of 186 IL21 Receptor products are currently listed.
CD360, il-21ra.a, IL21R, NILR
list all antibodies Gene Name GeneID UniProt
IL21R 50615 Q9HBE5
IL21R 60504 Q9JHX3
IL21R 308977  

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anti-Human IL21 Receptor Antibodies:

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anti-Rat (Rattus) IL21 Receptor Antibodies:

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Top referenced anti-IL21 Receptor Antibodies

  1. Human Monoclonal IL21 Receptor Primary Antibody for BCA - ABIN2663416 : Asao, Okuyama, Kumaki, Ishii, Tsuchiya, Foster, Sugamura: Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 8 references for 2663416

  2. Human Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4896191 : de Totero, Capaia, Fabbi, Croce, Meazza, Cutrona, Zupo, Loiacono, Truini, Ferrarini, Ferrini: Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells. in Experimental hematology 2010 (PubMed)
    Show all 5 references for 4896191

  3. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for BR, FACS - ABIN2663782 : Mehta, Wurster, Grusby: Biology of IL-21 and the IL-21 receptor. in Immunological reviews 2004 (PubMed)
    Show all 4 references for 2663782

  4. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for IF - ABIN2659037 : Jin, Carrio, Yu, Malek: Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 3 references for 2659037

  5. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN2658783 : Jin, Malek: Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21. in Journal of leukocyte biology 2006 (PubMed)
    Show all 3 references for 2658783

  6. Human Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4899489 : Ansén, Butler, Berezovskaya, Murray, Stevenson, Nadler, Hirano: Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 3 references for 4899489

  7. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4896193 : Caruso, Fina, Peluso, Fantini, Tosti, Del Vecchio Blanco, Paoluzi, Caprioli, Andrei, Stolfi, Romano, Ricci, MacDonald, Pallone, Monteleone: IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 references for 4896193

  8. Human Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4896189 : Zhang, Tao, Chopra, Dujmovic-Basuroski, Jin, Tang, Drulovic, Markovic-Plese: IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  9. Human Polyclonal IL21 Receptor Primary Antibody for IF (p), IHC (p) - ABIN748148 : Guan, Wang, Meng, Shi, Jiang, Xiao, Shi, Xu, Zhang: Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease. in Cytokine 2015 (PubMed)

  10. Human Polyclonal IL21 Receptor Primary Antibody for FACS, WB - ABIN4899487 : Alves, Arosa, van Lier: IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

More Antibodies against IL21 Receptor Interaction Partners

Horse (Equine) Interleukin 21 Receptor (IL21R) interaction partners

  1. IL21R is probably not causally involved in recurrent airway obstruction.

Human Interleukin 21 Receptor (IL21R) interaction partners

  1. bone marrow monocytes from multiple myeloma patients show distinct features compared to those from patients with indolent monoclonal gammopathies, supporting the role of IL21R over-expression by bone marrow CD14 (show NDUFA2 Antibodies)(+) cells in enhanced osteoclast formation.

  2. Report increased levels of IL-21R in the skeletal muscle endothelial cells of patients with peripheral arterial disease compared to control individuals.

  3. expression of IL-21 (show IL17C Antibodies) and IL-21R were up-regulated in autoimmune thyroid disease and may be involved in the pathogenesis of the disease through augmenting aberrant immune cascade

  4. interleukin-21 receptor deficiency is associated with Severe Combined Immunodeficiency (show PRKDC Antibodies).

  5. IL-21R on B cells is upregulated in allergic rhinitis patients when compared to controls. IL-21/IL-21R may be involved in the regulation of allergic reactions through the inhibition of IgE.

  6. IL-21 (show IL17C Antibodies)/IL-21R could act as potential biomarkers presenting early systemic sclerosis skin lesions severity.

  7. STAT3 (show STAT3 Antibodies) signaling downstream of IL-23R (show IL23R Antibodies) and IL-21R has a role in controlling human mucosal-associated invariant T cells and NKT (show SLC22A6 Antibodies) cell numbers

  8. Human neutrophils in peripheral blood express functional IL-21 (show IL17C Antibodies) receptors.

  9. IL-21R gene polymorphisms and serum IL-21 (show IL17C Antibodies) levels predict virological response to interferon (show IFNA Antibodies)-based therapy in Asian chronic hepatitis C patients.

  10. Abundant expression of interleukin-21 receptor in follicular lymphoma cells is associated with more aggressive disease.

Mouse (Murine) Interleukin 21 Receptor (IL21R) interaction partners

  1. natural genetic variation in murine Il21r influences neuronal cell viability after ischemia by modulating receptor function and downstream signal transduction

  2. IL-21 (show IL21 Antibodies) may play an important role in the pathogenesis of SSc (show CYP11A1 Antibodies) as a Th17 effector cytokine, and IL-21 (show IL21 Antibodies) may induce the differentiation of Th17 cells in the BLM-induced systemic sclerosis mouse model via Il21R.

  3. Gene expression analyses of angioimmunoblastic T-cell lymphoma (AITL), showed that essentially all cases expressed elevated levels of transcripts for IL21 (show IL21 Antibodies), IL21R, and a series of genes associated with TFH cell development and function.

  4. IIl21r deletion reduced spontaneous EAE associated with defective Th17 cell generation. IL-21R deficiency limited IL-23R (show IL23R Antibodies) expression on Th17 cells and inhibited expression of key molecules for pathogenic Th17 cell generation.

  5. our data demonstrate the novel finding that the IL-21R plays a critical role in regulating innate immune responses against HSV-2 infection.

  6. During experimental arthritis, IL-21R deficiency protected against severe inflammation and joint destruction. This was accompanied by suppressed serum IgG1 levels and antigen-specific T cell responses.

  7. in the absence of IL-21 (show IL21 Antibodies)/IL-21R signaling, Il2 (show IL2 Antibodies)(-/-) mice retained a deficiency in Tregs yet exhibited a reduced and delayed inflammatory disease which was reflected in reduced pancreatitis and hemolytic anemia

  8. IL-21R expression on donor CD4 (show CD4 Antibodies)+ T cells is essential for sustaining T cell number and help for B cells, resulting in more severe lupus-like renal disease, but it does not alter the balance of T helper (Th)17 cells and regulatory T cells.

  9. IL-21R controls both antigen transport by DCs and the crucial beacon (show UBL5 Antibodies) function of CD4 (show CD4 Antibodies)(+) cells for autoreactive CD8 (show CD8A Antibodies)(+) cells to reach the islets.

  10. Data indicate that CD8KO recipients given either C57Bl/6 or IL-21RKO CD8 (show CD8A Antibodies)+ cells showed the recipients given C57Bl/6 CD8 (show CD8A Antibodies)+ cells with significantly greater myocarditis than recipients of IL-21RKO CD8 (show CD8A Antibodies)+ cells.

IL21 Receptor (IL21R) Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with IL21 Receptor (IL21R)

  • interleukin 21 receptor (IL21R) antibody
  • interleukin 21 receptor (il21r) antibody
  • interleukin 21 receptor (Il21r) antibody
  • CD360 antibody
  • il-21ra.a antibody
  • IL21R antibody
  • NILR antibody

Protein level used designations for IL21R

interleukin-21 receptor , interleukin 21 receptor , interleukin 21 receptor alpha.a , IL-21 receptor , novel interleukin receptor , IL-21R , LR-beta , NR8 , lymphocyte receptor beta , novel cytokine receptor 8

416586 Gallus gallus
454006 Pan troglodytes
608011 Canis lupus familiaris
705759 Macaca mulatta
100066814 Equus caballus
100134976 Danio rerio
100450175 Pongo abelii
100467688 Ailuropoda melanoleuca
100601027 Nomascus leucogenys
50615 Homo sapiens
60504 Mus musculus
617967 Bos taurus
308977 Rattus norvegicus
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