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|Application / Reactivity||Mouse (Murine)|
|Blocking Antibody (Inhibition)||2 Antibodies|
|ELISA (Capture)||2 Antibodies|
|ELISA (Detection)||1 Antibodies|
|ELISpot (Capture) (ELISPOT (Capture))||1 Antibodies|
|Enzyme Immunoassay (EIA)||3 Antibodies|
|Flow Cytometry (FACS)||30 Antibodies|
|Functional Studies (Func)||4 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||6 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||5 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||5 Antibodies|
|Immunoprecipitation (IP)||2 Antibodies|
|Intracellular Staining (ICS)||6 Antibodies|
|Antigen||Interleukin 5 (IL5) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This IL5 antibody is un-conjugated Alternatives|
Functional Studies (Func), Flow Cytometry (FACS)
|9 references available|
|Supplier||Log in to see|
Product Details anti-IL5 AntibodyTarget Details IL5 Application Details Handling References for anti-IL5 Antibody (ABIN2665178) Images
|Purification||The antibody was purified by affinity chromatography.|
Target Details IL5Product Details anti-IL5 Antibody Application Details Handling References for anti-IL5 Antibody (ABIN2665178) Images back to top
|Alternative Name||IL-5 (IL5 Antibody Abstract)|
|Background||IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.|
|Research Area||Cytokines, Immunology, Virology, Inflammation, Cancer|
Application DetailsProduct Details anti-IL5 Antibody Target Details IL5 Handling References for anti-IL5 Antibody (ABIN2665178) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL5 Antibody Target Details IL5 Application Details References for anti-IL5 Antibody (ABIN2665178) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-IL5 Antibody (ABIN2665178)Product Details anti-IL5 Antibody Target Details IL5 Application Details Handling Images back to top
Sitkauskiene, Rådinger, Bossios et al.: "Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9." in: Respiratory research, Vol. 6, pp. 33, 2005 (PubMed).
Fan, Kouda, Nakamura et al.: "Effects of dietary restriction on spontaneous dermatitis in NC/Nga mice." in: Experimental biology and medicine (Maywood, N.J.), Vol. 226, Issue 11, pp. 1045-50, 2001 (PubMed).
Karulin, Hesse, Tary-Lehmann et al.: "Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1862-72, 2000 (PubMed).
Assenmacher, Schmitz, Radbruch: "Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells." in: European journal of immunology, Vol. 24, Issue 5, pp. 1097-101, 1994 (PubMed).
Takatsu, Tominaga, Harada et al.: "T cell-replacing factor (TRF)/interleukin 5 (IL-5): molecular and functional properties." in: Immunological reviews, Vol. 102, pp. 107-35, 1988 (PubMed).
Swain, Weinberg, English et al.: "IL-4 directs the development of Th2-like helper effectors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 145, Issue 11, pp. 3796-806, 1991 (PubMed).
Takatsu: "Interleukin 5 (IL-5) and its receptor." in: Microbiology and immunology, Vol. 35, Issue 8, pp. 593-606, 1992 (PubMed).
Takatsu: "Interleukin-5." in: Current opinion in immunology, Vol. 4, Issue 3, pp. 299-306, 1992 (PubMed).
Abrams, Roncarolo, Yssel et al.: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).
ImagesProduct Details anti-IL5 Antibody Target Details IL5 Application Details Handling References for anti-IL5 Antibody (ABIN2665178) back to top