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anti-Human IL7R antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL7R Antibody (supplied by: Log in to see )

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • CD127
  • CDW127
  • IL-7R-alpha
  • IL-7RA
  • IL-7Ralpha
  • IL7R
  • IL7RA
  • ILRA
Epitope
pTyr449
24
18
13
13
11
6
6
5
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
227
188
27
3
Host
Rabbit
153
105
98
13
2
Clonality
Polyclonal
Conjugate
This IL7R antibody is un-conjugated
26
24
22
16
15
14
10
9
9
7
7
6
6
5
5
5
5
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
170
157
66
65
51
22
13
12
12
9
5
4
4
4
3
3
2
2
2
1
1
Supplier
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Catalog No. ABIN372989
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN801438 IF (p) IHC (p) WB Rabbit IgG AA 440-451, pTyr449 Log in to see Polyclonal
0.0008982679 ABIN731063 IF (p) IHC (p) WB Rabbit IgG AA 250-300 Log in to see Polyclonal
0.0008982679 ABIN1859442 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 173-260 Log in to see Polyclonal
0.0008982679 ABIN801447 IHC (p) WB HRP Rabbit IgG AA 440-451, pTyr449 Log in to see Polyclonal
0.0008982679 ABIN731072 IHC (p) WB HRP Rabbit IgG AA 250-300 Log in to see Polyclonal
0.0008982679 ABIN731065 IHC (p) WB Biotin Rabbit IgG AA 250-300 Log in to see Polyclonal
0.0008982679 ABIN801440 IHC (p) WB Biotin Rabbit IgG AA 440-451, pTyr449 Log in to see Polyclonal
0.0008982679 ABIN4325441 FACS IHC IHC (p) WB Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4325442 FACS IHC IHC (p) WB Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226090 IHC IHC (p) WB Allophycocyanin Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226091 IHC IHC (p) WB Biotin Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226092 IHC IHC (p) WB DyLight 650 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226093 IHC IHC (p) WB DyLight 680 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226128 IHC IHC (p) WB Alexa Fluor 488 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226129 IHC IHC (p) WB Alexa Fluor 647 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226130 IHC IHC (p) WB Alexa Fluor 700 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226097 IHC IHC (p) WB PerCP Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226094 IHC IHC (p) WB DyLight 488 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226096 IHC IHC (p) WB DyLight 755 Mouse IgG2b lambda Log in to see 22F3D9
0.0008982679 ABIN4226100 IHC IHC (p) WB DyLight 405 Mouse IgG2b lambda Log in to see 22F3D9

Similar anti-IL7R Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 7 Antibodies 38 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Western Blotting (WB) 15 Antibodies
Biochemical Assay (BCA) 1 Antibodies
Blocking Reagent (BR) 3 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 4 Antibodies
Flow Cytometry (FACS) 87 Antibodies
Functional Studies (Func) 3 Antibodies

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Epitope pTyr449
(24), (18), (13), (13), (11), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(227), (188), (27), (3)
Host Rabbit
(153), (105), (98), (13), (2)
Clonality
Polyclonal
Conjugate This IL7R antibody is un-conjugated
(26), (24), (22), (16), (15), (14), (10), (9), (9), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(170), (157), (66), (65), (51), (22), (13), (12), (12), (9), (5), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1)
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Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling Images
Specificity This antibody recognizes Interleukin 7 Receptor Alpha Chain (IL7R). This phospho-specific polyclonal antibody reacts with Mouse IL-7 pY449 and shows minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide.
Cross-Reactivity (Details) Species reactivity (expected):Human, Rat.
Species reactivity (tested):Mouse.
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide corresponding to residues near Tyr449 of Mouse IL-7 protein

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD127 / IL7R (IL7R Antibody Abstract)
Background Interleukin 7 Receptor (IL7R) is a receptor for interleukin 7 (IL7). The function of IL7R requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).Synonyms: IL-7R-alpha, IL7 receptor alpha, Interleukin-7 receptor subunit alpha
Gene ID 3575
NCBI Accession NP_002176
UniProt P16871
Research Area CD Antigens, Surface Receptors of Immune Cells, Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling Images back to top
Application Notes Immunohistochemistry on paraffin sections: 5 μg/mL. Western blot: 1/1000 - 1/10000. ELISA: 1/100000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details Images back to top
Concentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, pH 7.2 with 0.15 M Sodium Chloride, 0.01 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Images

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling back to top
Supplier Images
 image for anti-IL7R antibody (Interleukin 7 Receptor) (pTyr449) (ABIN372989) anti-Interleukin 7 Receptor (IL7R) (pTyr449) antibody