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anti-Mouse (Murine) IL7R antibody for Biochemical Assay

Recommended IL7R Antibody (supplied by: Log in to see )

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • CD127
  • CDW127
  • IL-7R-alpha
  • IL-7RA
  • IL-7Ralpha
  • IL7R
  • IL7RA
  • ILRA
Reactivity
Mouse (Murine)
163
146
27
3
Host
Rat
94
92
67
12
2
Clonality
Monoclonal
Conjugate
This IL7R antibody is un-conjugated
25
20
17
16
10
10
9
9
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Biochemical Assay (BCA)
118
90
64
24
22
13
12
12
11
9
5
4
4
4
3
3
2
2
2
1
1
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Catalog No. ABIN2664191
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Top referenced anti-IL7R antibody for Biochemical Assay

Similar anti-IL7R Antibodies

Application / Reactivity Mouse (Murine)
Biochemical Assay (BCA) 1 Antibodies
Blocking Reagent (BR) 3 Antibodies
ELISA 37 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 4 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 69 Antibodies
Functional Studies (Func) 3 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Intracellular Flow Cytometry (ICFC) 12 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Western Blotting (WB) 51 Antibodies

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Reactivity Mouse (Murine)
(163), (146), (27), (3)
Host Rat
(94), (92), (67), (12), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL7R antibody is un-conjugated
(25), (20), (17), (16), (10), (10), (9), (9), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Biochemical Assay (BCA)
(118), (90), (64), (24), (22), (13), (12), (12), (11), (9), (5), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling References for anti-IL7R Antibody (ABIN2664191) Images
Purification The antibody was purified by affinity chromatography.
Clone A7R34
Isotype IgG2a kappa

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling References for anti-IL7R Antibody (ABIN2664191) Images back to top
Antigen
Alternative Name CD127 (IL7R Antibody Abstract)
Background CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling References for anti-IL7R Antibody (ABIN2664191) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details References for anti-IL7R Antibody (ABIN2664191) Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL7R Antibody (ABIN2664191)

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling Images back to top
Background publications

Mazzon, Anselmo, Cibella, Soldani, Destro, Kim, Roncalli, Burden, Dustin, Sarukhan, Viola: "The critical role of agrin in the hematopoietic stem cell niche." in: Blood, Vol. 118, Issue 10, pp. 2733-42, 2011

Taylor, Patel, Lin, Butler, Lake, Newberry, Williams: "Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patches." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 9, pp. 5659-67, 2007

Pillai, Torok-Storb, Iwata: "Expression and function of IL-7 receptors in marrow stromal cells." in: Leukemia & lymphoma, Vol. 45, Issue 12, pp. 2403-8, 2004

Hashi, Yoshida, Honda, Fraser, Kubo, Awane, Takabayashi, Nakano, Yamaoka, Nishikawa: "Compartmentalization of Peyer's patch anlagen before lymphocyte entry." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 6, pp. 3702-9, 2001

Sudo, Nishikawa, Ohno, Akiyama, Tamakoshi, Yoshida, Nishikawa: "Expression and function of the interleukin 7 receptor in murine lymphocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 19, pp. 9125-9, 1993

Images

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling References for anti-IL7R Antibody (ABIN2664191) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL7R antibody (Interleukin 7 Receptor) (ABIN2664191) anti-Interleukin 7 Receptor (IL7R) antibody