anti-Mouse (Murine) LIF antibody for Enzyme Immunoassay

Recommended LIF Antibody (supplied by: Log in to see )

Antigen
Leukemia Inhibitory Factor (LIF) Antibodies
  • CDF
  • DIA
  • HILDA
  • MLPLI
  • A230075M04Rik
  • AW061234
  • LIF
  • leukemia inhibitory factor
  • leukemia inhibitory factor (cholinergic differentiation factor)
  • leukemia inhibitory factor receptor
  • Lif
  • LIF
  • Lifr
Epitope
Center
15
14
9
7
6
6
4
4
4
3
3
3
3
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
148
84
30
11
7
6
5
2
2
2
1
1
Host
Rabbit
95
49
37
6
2
2
Clonality
Polyclonal
Conjugate
This LIF antibody is un-conjugated
7
6
6
6
6
5
5
4
3
3
3
3
3
3
3
3
3
3
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
141
48
45
45
43
6
5
4
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN5554270
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1449476 EIA WB Goat Internal Region, AA 28-39 Log in to see Polyclonal

General

Antigen Leukemia Inhibitory Factor (LIF) Antibodies
Epitope Center
(15), (14), (9), (7), (6), (6), (4), (4), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(148), (84), (30), (11), (7), (6), (5), (2), (2), (2), (1), (1)
Host Rabbit
(95), (49), (37), (6), (2), (2)
Clonality
Polyclonal
Conjugate This LIF antibody is un-conjugated
(7), (6), (6), (6), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(141), (48), (45), (45), (43), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1)
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Product Details anti-LIF Antibody

Target Details LIF Application Details Handling Images
Specificity This antibody detects Leukemia inhibitory factor at Center.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Immunogen 16 amino acid peptide near the center of human LIF

Target Details LIF

Product Details anti-LIF Antibody Application Details Handling Images back to top
Antigen
Alternative Name Leukemia Inhibitory Factor (LIF Antibody Abstract)
Background LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.Synonyms: D factor, Differentiation-stimulating factor, Emfilermin, HILDA, LIF, MLPLI, Melanoma-derived LPL inhibitor
Gene ID 3976
NCBI Accession NP_002300
UniProt P15018
Research Area Cancer
Pathways JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding

Application Details

Product Details anti-LIF Antibody Target Details LIF Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-LIF Antibody Target Details LIF Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.