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Browse our PIAS1 Proteins (PIAS1)

Full name:
Protein Inhibitor of Activated STAT, 1 Proteins (PIAS1)
On are 7 Protein Inhibitor of Activated STAT, 1 (PIAS1) Proteins from 4 different suppliers available. Additionally we are shipping PIAS1 Antibodies (91) and PIAS1 Kits (25) and many more products for this protein. A total of 132 PIAS1 products are currently listed.
2900068C24Rik, ddxbp1, gbp, GU/RH-II, pias, pias1-A, xPAIS1, xPIAS1, zmiz3
list all proteins Gene Name GeneID UniProt
PIAS1 56469 O88907
PIAS1 8554 O75925
Rat PIAS1 PIAS1 300772  

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PIAS1 Proteins (PIAS1) by Origin

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Top referenced PIAS1 Proteins

  1. Human PIAS1 Protein expressed in Wheat germ - ABIN1314985 : Chen, Hsu, Ma, Tai, Lee: CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 (PubMed)

More Proteins for PIAS1 Interaction Partners

Mouse (Murine) Protein Inhibitor of Activated STAT, 1 (PIAS1) interaction partners

  1. Pias1 expression in primary myoblasts enhances the induction of cardiac muscle genes MyoD (show MYOD1 Proteins), Myogenin (show MYOG Proteins) and Myomaker. Endothelial cell specific inactivation of Pias1 in vivo impairs yolk sac (show ADCY10 Proteins) erythrogenesis, angiogenesis and recapitulates loss of myocardium muscle mass. Pias1 is an essential gene for YS erythropoiesis and vasculogenesis in vivo.

  2. Data suggest overexpression of Pias1 in white adipose tissue (WAT) of obesity/prediabetes improves insulin (show INS Proteins) resistance; knockdown of Pias1 in normal WAT leads to insulin (show INS Proteins) resistance; Pias1 expression in WAT is down-regulated by c-Jun N-terminal kinase.

  3. Between the E3 SUMO ligase PIAS1 and STAT-3 (show STAT3 Proteins).

  4. Knockdown of PIAS1 in astrocytes impairs the accumulation of nuclear STI1 (show STIP1 Proteins) in response to irradiation. Moreover, a PIAS1 mutant lacking the STI1 (show STIP1 Proteins) binding site is unable to increase STI1 (show STIP1 Proteins) nuclear retention.

  5. A novel role of PIAS1 in maintaining the quiescence of dormant hematopoietic stem cells and in the epigenetic repression of the myeloerythroid program.

  6. The present study showed that PIAS1 functions as a SUMO E3 ligase of C/EBPbeta (show CEBPB Proteins) to regulate adipogenesis.

  7. Piasy (show PIAS4 Proteins) represses the synergistic activation of PITX2 (show PITX2 Proteins) with interacting co-factors and Piasy (show PIAS4 Proteins) represses Pias1 activation of PITX2 (show PITX2 Proteins) transcriptional activity.

  8. MAPK-activated protein kinase-2 limits endothelial inflammation via the PIAS1 S522 phosphorylation-mediated increase in PIAS1 transrepression and SUMO ligase activity.

  9. Results suggest that PIAS1 may serve as a lipogenic regulator by negatively modulating liver X receptors (LXRs) in a SUMOylation-independent manner.

  10. PIAS1 modifies covalent modification of Blimp-1 (show PRDM1 Proteins) by SUMO-1 (show SUMO1 Proteins) at lysine 816.

Human Protein Inhibitor of Activated STAT, 1 (PIAS1) interaction partners

  1. identified the SUMO ligase PIAS1 as a constituent PML (show PML Proteins)-NB antiviral protein. This finding distinguishes a SUMO ligase that may mediate signaling events important in promyelocytic leukemia (show PML Proteins) nuclear body mediated intrinsic immunity.

  2. PIAS1 enhances p300 (show EP300 Proteins) recruitment to c-Myb (show MYB Proteins)-bound sites through interaction with both proteins. In addition, the E3 activity of PIAS1 enhances further its coactivation

  3. Results show that apocrine breast cancer and prostate cancer cells share a core AR cistrome and target gene signature linked to cancer cell growth, and PIAS1 plays a similar coregulatory role for AR in both cancer cell types.

  4. c-Myc (show MYC Proteins) is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 (show SENP7 Proteins) and RNF4 (show RNF4 Proteins)

  5. Data demonstrate that PIAS1 interacts with TRF2 (show TERF2 Proteins) and mediates its sumoylation serving as a molecular switch that controls the level of TRF2 (show TERF2 Proteins) at telomeres.

  6. the expression of SENP8 (show SENP8 Proteins), SAE1 (show SAE1 Proteins), PIAS1, PIAS2 (show PIAS2 Proteins) and ZMIZ1 is deregulated in the majority of PTC (show F9 Proteins) tissues, likely contributing to the PTC (show F9 Proteins) phenotype.

  7. Our data suggest that necdin suppresses PIAS1 both by inhibiting SUMO E3 ligase activity and by promoting ubiquitin-dependent degradation.

  8. the presented data indicate that PIAS1 is crucial for parental and docetaxel resistant prostate cancer cell survival

  9. Elevated PIAS1 expression was observed in breast tumor samples.

  10. PIAS1 is the E3 ligase responsible for SUMOylation of HMGN2 (show HMGN2 Proteins).

PIAS1 Protein Profile

Protein Summary

This gene encodes a member of the mammalian PIAS

Alternative names and synonyms associated with PIAS1

  • protein inhibitor of activated STAT, 1 (LOC100232805)
  • protein inhibitor of activated STAT 1 (Pias1)
  • protein inhibitor of activated STAT, 1 (PIAS1)
  • protein inhibitor of activated STAT, 1 (Pias1)
  • protein inhibitor of activated STAT, 1 (pias1)
  • 2900068C24Rik protein
  • ddxbp1 protein
  • gbp protein
  • GU/RH-II protein
  • pias protein
  • pias1-A protein
  • xPAIS1 protein
  • xPIAS1 protein
  • zmiz3 protein

Protein level used designations for PIAS1

protein inhibitor of activated STAT, 1 , DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1 , DEAD/H box-binding protein 1 , E3 SUMO-protein ligase PIAS1 , protein inhibitor of activated STAT protein 1 , AR interacting protein , RNA helicase II-binding protein , gu-binding protein , protein inhibitor of activated STAT-1 , zinc finger, MIZ-type containing 3 , SUMO E3 ligase

100232805 Taeniopygia guttata
56469 Mus musculus
8554 Homo sapiens
300772 Rattus norvegicus
564496 Danio rerio
373715 Xenopus laevis
427514 Gallus gallus
478350 Canis lupus familiaris
509231 Bos taurus
100339509 Oryctolagus cuniculus
100729878 Cavia porcellus
100519005 Sus scrofa
101104493 Ovis aries
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