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anti-Mouse (Murine) Prolactin antibody for Immunohistochemistry (Frozen Sections)

Recommended Prolactin Antibody (supplied by: Log in to see )

Antigen
Prolactin (PRL) Antibodies
  • AV290867
  • prl
  • PRL
  • Prl1a1
  • PRLB
  • PRLSD1
  • Prol
  • prolactin
  • RATPRLSD1
  • RNPROL
Epitope
C-Term
22
22
20
16
14
14
13
11
10
10
9
8
7
7
6
6
6
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
442
68
48
13
13
3
2
2
1
1
1
1
Host
Rabbit
292
224
5
1
1
Clonality
Polyclonal
Conjugate
This Prolactin antibody is un-conjugated
35
29
29
24
21
21
4
4
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
355
186
78
64
39
38
27
27
26
23
12
11
9
8
8
5
4
4
2
2
2
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN493382
$ 456.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088254584 ABIN493380 EIA IHC (fro) WB Rabbit IgG N-Term Log in to see Polyclonal
0.00088254584 ABIN1078459 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 1-226 Log in to see Polyclonal
0.00088254584 ABIN958232 IHC (fro) Neut ELISA WB Goat IgG Log in to see Polyclonal
0.00088254584 ABIN190028 IHC (fro) ELISA WB Mouse IgG1 Log in to see 6F11
0.00088254584 ABIN3209809 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal

Similar anti-Prolactin Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Confocal Microscopy (CM) 4 Antibodies 4 Antibodies
ELISA 43 Antibodies 21 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 6 Antibodies
Immunofluorescence (IF) 6 Antibodies 4 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 14 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies
Western Blotting (WB) 24 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen Prolactin (PRL) Antibodies
Epitope C-Term
(22), (22), (20), (16), (14), (14), (13), (11), (10), (10), (9), (8), (7), (7), (6), (6), (6), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(442), (68), (48), (13), (13), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(292), (224), (5), (1), (1)
Clonality
Polyclonal
Conjugate This Prolactin antibody is un-conjugated
(35), (29), (29), (24), (21), (21), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(355), (186), (78), (64), (39), (38), (27), (27), (26), (23), (12), (11), (9), (8), (8), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-Prolactin Antibody

Target Details Prolactin Application Details Handling Images
Specificity Recognizes Prolactin (C-term). The Anti-Prolactin antibodies have been fully characterized for cross reactivity with other species Prolactin molecules and for other cellular proteins using Western blot analyses.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse and Rat.
Purification Affinity Chromatography on immobilized antigen
Immunogen Synthetic peptide corresponding to C-terminal of Human Prolactin.
Isotype IgG

Target Details Prolactin

Product Details anti-Prolactin Antibody Application Details Handling Images back to top
Antigen
Alternative Name Prolactin / PRL (PRL Antibody Abstract)
Background Prolactin is synthesis starts in first few weeks of gestation in pituitary lactotropes and serum levels decline shortly after birth. Prolactin levels rise significantly during pregnancy. Other factors that regulate Prolactin levels include sleep, stress, hypoglycemia and exercise. Prolactin is structurally related to growth hormone and placental lactogen. The genes for these hormone share common structural homology, prolactin is coded by a single gene located on human chromosome 6. The prolactin s a single polypeptide of 199 amino acids with a molecular mass of 23 kDa and has 2 disulfide bond, one more than GH. Majority of Prolactin is in circulation in monomeric form (23 kDa). Unlike GH, the prolactin is glycosylated at asparagine. Some dimeric, polymeric and degraded form of prolactin is also detectable in circulation, but their physiological significance is not known. Prolactin binds to two prolactin receptors, with downstream signal transduction mediated by tyrosine kinase cascade. Physiological effects include breast development, and effects on hypothalamus-pituitary-gonadal axis. Prolactin receptor are also present in T lymphocytes, and prolactin has been shown to modulate immune responses (1). Prolactin secreting tumors are common cause of hyperprolactinemia, in women the symptoms relate to galactorrhea, amenorrhea and infertility. In men the symptoms include galactorrhea, infertility and impotance.
Gene ID 5617
NCBI Accession NP_000939
UniProt P01236
Pathways JAK-STAT Signaling

Application Details

Product Details anti-Prolactin Antibody Target Details Prolactin Handling Images back to top
Application Notes This antibody is ideal for ELISA and Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Prolactin Antibody Target Details Prolactin Application Details Images back to top
Concentration 0.68 mg/mL
Buffer Stabilization buffer with 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at-20 °C.

Images

Product Details anti-Prolactin Antibody Target Details Prolactin Application Details Handling back to top
Supplier Images
 image for anti-Prolactin antibody (PRL) (C-Term) (ABIN493382) anti-Prolactin (PRL) (C-Term) antibody