You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) PTPN6 antibody for Western Blotting

Recommended PTPN6 Antibody (supplied by: Log in to see )

Antigen
Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
  • SHP
  • SHP-1
  • Shp1
  • HCP
  • HCPH
  • HPTP1C
  • PTP-1C
  • SH-PTP1
  • SHP-1L
  • SHP1
  • Hcph
  • Ptp1C
  • hcp
  • me
  • motheaten
  • Ptph6
  • Shp-1
  • DRPLA
  • protein tyrosine phosphatase, non-receptor type 6
  • nuclear receptor subfamily 0, group B, member 2
  • PTPN6
  • Nr0b2
  • Ptpn6
Epitope
AA 492-597
26
23
15
8
8
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
183
90
85
6
3
2
2
2
1
1
1
1
1
Host
Mouse
119
33
32
Clonality
Monoclonal
Conjugate
This PTPN6 antibody is un-conjugated
7
7
7
3
3
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
134
77
54
30
29
27
9
8
6
5
4
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN967767
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0923712 ABIN967766 IF IP IHC WB Mouse IgG1 AA 492-597 Log in to see 52-PTP1C-SHP1 5
3.0923712 ABIN188850 ELISA WB Goat Log in to see Polyclonal 1
3.0923712 ABIN2788789 WB Rabbit Middle Region Log in to see Polyclonal
3.0923712 ABIN1531195 IHC ELISA WB Rabbit IgG pTyr536 Log in to see Polyclonal
3.0923712 ABIN3182468 ELISA IHC WB Rabbit IgG pTyr536 Log in to see Polyclonal
3.0923712 ABIN3186951 ELISA IHC WB Rabbit IgG Thr47 Log in to see Polyclonal
3.0923712 ABIN1532211 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN2465285 ELISA WB Goat Internal Region Log in to see Polyclonal
3.0923712 ABIN442153 IHC IHC (p) IP WB Rabbit IgG Center Log in to see Polyclonal
3.0923712 ABIN1874455 IF IHC WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN4348609 IP WB Rabbit Log in to see NL213
3.0923712 ABIN3021975 IHC WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN711641 IF (p) IHC (p) WB Rabbit IgG pSer591 Log in to see Polyclonal
3.0923712 ABIN2564808 ELISA WB Goat IgG Internal Region Log in to see Polyclonal
3.0923712 ABIN2422133 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN2428691 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN2404230 IF IHC WB Rabbit IgG Log in to see Polyclonal
3.0923712 ABIN1845593 IHC WB Rabbit pTyr536 Log in to see Polyclonal
3.0923712 ABIN1845595 IHC WB Rabbit Log in to see Polyclonal
3.0923712 ABIN274221 IF IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-PTPN6 antibody for Western Blotting

Similar anti-PTPN6 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 19 Antibodies 20 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 18 Antibodies 18 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies 26 Antibodies
Immunohistochemistry (IHC) 40 Antibodies 41 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies 15 Antibodies
Immunoprecipitation (IP) 4 Antibodies 6 Antibodies
Western Blotting (WB) 50 Antibodies 53 Antibodies

General

Antigen Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
Epitope AA 492-597
(26), (23), (15), (8), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(183), (90), (85), (6), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(119), (33), (32)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PTPN6 antibody is un-conjugated
(7), (7), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(134), (77), (54), (30), (29), (27), (9), (8), (6), (5), (4), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-PTPN6 Antibody

Target Details PTPN6 Application Details Handling References for anti-PTPN6 Antibody (ABIN967767) Images
Cross-Reactivity Dog (Canine), Rat (Rattus), Mouse (Murine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human PTP1C aa.. 492-597
Clone 52-PTP1C-SHP1
Isotype IgG1

Target Details PTPN6

Product Details anti-PTPN6 Antibody Application Details Handling References for anti-PTPN6 Antibody (ABIN967767) Images back to top
Antigen
Alternative Name PTP1C (PTPN6 Antibody Abstract)
Background PTP1C (SH-PTP1, SHP-1, or HCP) is a protein-tyrosine phosphatase (PTP) that is expressed in epithelial and hematopoietic cells. It contains two N-terminal SH2 domains and a C-terminal phosphatase domain. While its distribution is primarily cytosolic, exposure to various stimuli induces movement of PTP1C to other cellular locations to allow interaction with its substrates. This enzyme associates with the IL-3, IL-4, erythropoietin, and stem cell factor receptors and may regulate their signaling pathways by dephosphorylation of their receptors or their downstream effectors. Motheaten mice, which possess a nonfunctional PTP1C gene, display multiple hematopoietic abnormalities including increased proliferation and activation of myeloid cells. Studies involving these mice have clearly implicated PTP1C in negative regulation of CSF-1 (colony stimulating factor-1) mitogenic signaling and have demonstrated a role for PTP1C as an intermediate between Ras and the MAP kinase pathway.
Molecular Weight 68 kDa
Pathways JAK-STAT Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-PTPN6 Antibody Target Details PTPN6 Handling References for anti-PTPN6 Antibody (ABIN967767) Images back to top
Comment

Related Products: ABIN968537, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details References for anti-PTPN6 Antibody (ABIN967767) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.

References for anti-PTPN6 Antibody (ABIN967767)

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Handling Images back to top
Product cited in:

Duchene, Schanstra, Pecher, Pizard, Susini, Esteve, Bascands, Girolami: "A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40375-83, 2002

Keilhack, Müller, Böhmer, Frank, Weidner, Birchmeier, Ligensa, Berndt, Kosmehl, Günther, Müller, Birchmeier, Böhmer: "Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1." in: The Journal of cell biology, Vol. 152, Issue 2, pp. 325-34, 2001

Lund-Johansen, Davis, Bishop, de Waal Malefyt: "Flow cytometric analysis of immunoprecipitates: high-throughput analysis of protein phosphorylation and protein-protein interactions." in: Cytometry, Vol. 39, Issue 4, pp. 250-9, 2000

Liu, Hill, Chernoff: "Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)." in: The Journal of biological chemistry, Vol. 271, Issue 49, pp. 31290-5, 1997

Kenner, Anyanwu, Olefsky, Kusari: "Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling." in: The Journal of biological chemistry, Vol. 271, Issue 33, pp. 19810-6, 1996

Images

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Handling References for anti-PTPN6 Antibody (ABIN967767) back to top
Supplier Images
Western Blotting (WB) image for anti-PTPN6 antibody (Protein-tyrosine Phosphatase 1C) (AA 492-597) (ABIN967767) Western blot analysis of PTP1C on Jurkat cell lysate. Lane 1: 1:500, lane 2: 1:1000, ...
Immunofluorescence (IF) image for anti-PTPN6 antibody (Protein-tyrosine Phosphatase 1C) (AA 492-597) (ABIN967767) Immunofluorescent staining on HL60 cells.
 image for anti-PTPN6 antibody (Protein-tyrosine Phosphatase 1C) (AA 492-597) (ABIN967767) anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 492-597) antibody (Image 3)
Western Blotting (WB) image for anti-PTPN6 antibody (Protein-tyrosine Phosphatase 1C) (AA 492-597) (ABIN967767) anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 492-597) antibody (Image 4)