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anti-Pig (Porcine) SOCS4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS4 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 4 (SOCS4) Antibodies
  • 3110032M18Rik
  • A730004F22Rik
  • AI427843
  • AU015727
  • AU015859
  • SOCS4
  • socs4
  • Socs4
  • socs4a
  • SOCS6
  • socs6l
  • Socs7
  • socs7
  • SOCS7
  • wu:fb77f06
  • zgc:64107
Epitope
C-Term
27
22
21
16
15
5
3
3
3
2
2
1
1
1
Reactivity
Cow (Bovine), Human, Pig (Porcine)
82
3
3
3
1
1
1
Host
Goat
63
16
5
Clonality
Polyclonal
Conjugate
This SOCS4 antibody is un-conjugated
5
5
5
5
5
5
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
64
50
23
18
11
8
6
1
1
1
Supplier
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Catalog No. ABIN1109094
$ 379.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009015372 ABIN1739509 IHC (p) ELISA Goat C-Term Log in to see Polyclonal

Similar anti-SOCS4 Antibodies

Application / Reactivity Human Cow (Bovine) Pig (Porcine)
Western Blotting (WB) 62 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies 2 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 23 Antibodies 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 18 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 1 Antibodies 1 Antibodies
ELISA 48 Antibodies 2 Antibodies

General

Antigen Suppressor of Cytokine Signaling 4 (SOCS4) Antibodies
Epitope C-Term
(27), (22), (21), (16), (15), (5), (3), (3), (3), (2), (2), (1), (1), (1)
Reactivity Cow (Bovine), Human, Pig (Porcine)
(82), (3), (3), (3), (1), (1), (1)
Host Goat
(63), (16), (5)
Clonality
Polyclonal
Conjugate This SOCS4 antibody is un-conjugated
(5), (5), (5), (5), (5), (5)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(64), (50), (23), (18), (11), (8), (6), (1), (1), (1)
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Product Details anti-SOCS4 Antibody

Target Details SOCS4 Application Details Handling Images
Sequence C-SKVRVLRIDA PEQQ
Specificity This antibody detects SOCS-4 at C-term.
Cross-Reactivity (Details) Species reactivity (expected):Pig, Bovine.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide with sequence from the C Terminus of Human SOCS4 (NP_543143.1, NP_955453.1). Genename: SOCS4

Target Details SOCS4

Product Details anti-SOCS4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SOCS4 (SOCS4 Antibody Abstract)
Background Accumulating evidence has demonstrated that cytokine receptor signaling is negatively regulated by a family of Src homology 2 domain-containing adaptor molecules termed SOCS (Suppressor of Cytokine Signaling) (1-3). Currently, there are eight members of the SOCS family that have been recognized, SOCS-1, -2, -3, -4, - 5, -6, -7 and CIS. Structurally, the SOCS proteins are composed of an N-terminus region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C-terminus motif that has been called the SOCS box (4). The SOCS proteins appear to form part of a classical negative feed back loop that regulates cytokine signal transduction via a STATinduced transcriptional mechanism (5). Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. Within the SOCS subfamily, SOCS-4, SOCS-5, SOCS-6, SOCS-7 remain poorly understood (6). On the basis of structural considerations, it would be expected that SOCS-4, -5, -6, and -7, like SOCS-1, SOCS-2, SOCS-3 and CIS, act to negatively regulate signal transduction (4), but it is uncertain which specific cytokine is involved (7-9).Synonyms: SOCS-4, SOCS-7, SOCS7, Suppressor of cytokine signaling 4, Suppressor of cytokine signaling 7
Gene ID 122809
NCBI Accession NP_543143
UniProt Q8WXH5
Research Area Signaling
Pathways JAK-STAT Signaling, EGFR Signaling Pathway

Application Details

Product Details anti-SOCS4 Antibody Target Details SOCS4 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-SOCS4 Antibody Target Details SOCS4 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-SOCS4 Antibody Target Details SOCS4 Application Details Handling back to top
Supplier Images
 image for anti-SOCS4 antibody (Suppressor of Cytokine Signaling 4) (C-Term) (ABIN1109094) anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibody