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anti-Rat (Rattus) STAT3 antibody for Immunohistochemistry (Frozen Sections)

Recommended STAT3 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
  • signal transducer and activator of transcription 3 (acute-phase response factor)
  • signal transduction and activation of transcription 3
  • signal transducer and activator of transcription 3
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1
  • STAT3
  • stat3
  • Stat3
  • stat3.1
Epitope
phosphorylated
111
84
71
25
18
17
17
16
15
14
13
11
6
5
5
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
566
339
267
40
37
32
29
16
11
10
7
5
5
5
4
3
3
2
1
1
1
1
1
Host
Mouse
441
129
34
5
1
1
Clonality
Monoclonal
Conjugate
This STAT3 antibody is un-conjugated
25
22
18
14
11
11
9
6
4
4
4
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
516
234
216
82
76
76
58
54
27
12
11
8
8
6
5
3
3
3
2
2
2
1
1
1
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Catalog No. ABIN126899
$ 555.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1860649 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 135-279 Log in to see Polyclonal
1 ABIN2476595 IHC (fro) ELISA WB Goat IgG Log in to see Polyclonal 1

Top referenced anti-STAT3 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-STAT3 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine)
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies 4 Antibodies 4 Antibodies 1 Antibodies
Western Blotting (WB) 474 Antibodies 263 Antibodies 204 Antibodies 30 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies 1 Antibodies 1 Antibodies
Intracellular Staining (ICS) 12 Antibodies 12 Antibodies 4 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies 2 Antibodies 2 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 12 Antibodies 64 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
Epitope phosphorylated
(111), (84), (71), (25), (18), (17), (17), (16), (15), (14), (13), (11), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(566), (339), (267), (40), (37), (32), (29), (16), (11), (10), (7), (5), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1)
Host Mouse
(441), (129), (34), (5), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT3 antibody is un-conjugated
(25), (22), (18), (14), (11), (11), (9), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(516), (234), (216), (82), (76), (76), (58), (54), (27), (12), (11), (8), (8), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1)
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Product Details anti-STAT3 Antibody

Target Details STAT3 Application Details Handling Images
Specificity This antibody specifically recognizes STAT3 phosphorylated at Ser 727. The antibody does not crossreact with the non-phosphorylated form of STAT3 nor with unrelated serine-phosphorylated proteins.
Characteristics Synonyms: STAT-3, Acute-phase response factor, APRF, Signal transducer and activator oftranscription 3
Purification Size exclusion chromatography
Components incl. positive Control
Immunogen Synthetic phosphopeptide conjuagted to KLH
Clone 23G5
Isotype IgG1

Target Details STAT3

Product Details anti-STAT3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name STAT3 (STAT3 Antibody Abstract)
Background The STAT proteins serve as both cytoplasmic signal transducers and nuclear activators of transcription. STATs are mediators involved in cytokine signalling. In response to a specific cytokine signal, STAT proteins are phosphorylated on conserved tyrosine residues. Phosphorylated STAT proteins dimerize via their SH2 domains and move to the nucleus. The STAT dimers bind to specific DNA elements resulting in transcriptional regulation of downstream target genes. Besides tyrosine phosphorylation, STAT3 activity is regulated by serine phosphorylation at serine 727. Recent reports indicate that both MAP kinase and SAP kinase induce phosphorylaton at serine 727.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
Gene ID 6774
UniProt P40763
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-STAT3 Antibody Target Details STAT3 Handling Images back to top
Application Notes Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Images back to top
Reconstitution Restore with 1 mL H2O (15 min, RT).
Buffer 1 mL2 x PBS / 0.09 % Na-azide / PEG and Sucrose
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C/-80 °C
Storage Comment Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.
Expiry Date 12 months

Images

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (phosphorylated) (ABIN126899) anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (phosphorylated) antibody