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Browse our STAT6 Proteins (STAT6)

Full name:
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced Proteins (STAT6)
On www.antibodies-online.com are 14 Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Proteins from 7 different suppliers available. Additionally we are shipping STAT6 Antibodies (419) and STAT6 Kits (47) and many more products for this protein. A total of 495 STAT6 products are currently listed.
Synonyms:
D12S1644, IL-4-STAT, STAT6B, STAT6C
list all proteins Gene Name GeneID UniProt
STAT6 20852 P52633
STAT6 6778 P42226
STAT6 362896  

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STAT6 Proteins (STAT6) by Origin

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Top referenced STAT6 Proteins

  1. Human STAT6 Protein expressed in Baculovirus infected Insect Cells - ABIN2005539 : Litterst, Pfitzner: Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN2005539

More Proteins for STAT6 Interaction Partners

Mouse (Murine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. These data demonstrate that dysregulated IL-25 (show IL25 Proteins) expression contributes to lipid accumulation, whereas exogenous IL-25 (show IL25 Proteins) protects against hepatic steatosis through IL-13 (show IL13 Proteins) activation of STAT6.

  2. Grail (show RNF128 Proteins) interacts with Stat6 and targets it for ubiquitination and degradation in Th2 cells.

  3. The lack of STAT6 did not affect the ability of macrophages to change cytokine production reciprocally or to rescue mice from lethal endotoxemia.

  4. both in vivo and in vitro experiments demonstrate that the transcription factors STAT6 and KLF4 (show KLF4 Proteins) implement IL-4 (show IL4 Proteins)-induced M2 polarization via the dual catalytic activities of MCPIP (show ZC3H12A Proteins).

  5. Th2 immunity mediated by STAT6 appears to play a protective role in a murine model of prurigo

  6. Data suggest that transcription factor STAT6 regulates the recruitment of eosinophils to the lung during the development of allergic asthma.

  7. the cross talk between HDAC4 (show HDAC5 Proteins) and STAT6 is an important regulatory mechanism of Arg1 (show ARG1 Proteins) transcription in dendritic cells

  8. TSLP (show TSLP Proteins) induces mast cell development and aggravates allergic reactions through the activation of MDM2 (show MDM2 Proteins) and STAT6.

  9. These data show that IL-4 (show IL4 Proteins) and IL-13 (show IL13 Proteins) decrease kinin receptors in a STAT6-dependent mechanism, which can be one important mechanism by which these cytokines exert their anti-inflammatory effects and impair bone resorption

  10. T-cell-derived extrafollicular IL-4 (show IL4 Proteins)/IL-13 (show IL13 Proteins) and signal transducer and activator of transcription 6-regulated genes in B cells play a critical role for orchestration of the GC response in type 2 immunity.

Human Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. the majority of intrathoracic SFTs exhibited STAT6 nuclear staining, and NAB2ex4-STAT6ex2/3 was the predominant fusion type.

  2. Case Report: NAB2 (show NAB2 Proteins)-STAT6 fusion in glioblastoma.

  3. A constitutively activated form of STAT6 is able to bypass IL-4 (show IL4 Proteins) upstream signalling and instruct dendritic-cell-specific functional DNA methylation (show HELLS Proteins) changes

  4. interleukin-4 (show IL4 Proteins) regulates hematopoietic lineage choice by activating the JAK3 (show JAK3 Proteins)-STAT6 pathway, which causes dendritic-cell-specific DNA demethylation

  5. Immunohistochemistry results indicate that combination with ALDH1 (show ALDH1A1 Proteins) and STAT6 can improve the diagnostic value of CD34 (show CD34 Proteins) for solitary fibrous tumors.

  6. T allele of rs324011 in STAT6 would increase the risk of atopic dermatitis (AD) occurrence in children. Haplotypes of rs324011/rs167769 were also significantly associated with childhood AD in Taiwanese population.

  7. These results suggest that STAT6 plays an important role in regulating Sp1 (show PSG1 Proteins) and BCL6 (show BCL6 Proteins) through STAT2 (show STAT2 Proteins) to exert the anti-proliferative effects of type I IFN.

  8. We delineate the common and rare NAB2 (show NAB2 Proteins)-STAT6 fusion variants in solitary fibrous tumors

  9. STAT6 is a direct target of miR (show MLXIP Proteins)-361-5p and promotes Bcl-xL (show BCL2L1 Proteins) expression.

  10. This study confirms that meningeal Meningeal solitary fibrous tumor and hemangiopericytoma represent a histopathologic continuum linked by STAT6 nuclear expression and NAB2 (show NAB2 Proteins)-STAT6 fusion similar to their soft tissue counterparts.

Pig (Porcine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. Data show that IL-4 (show IL4 Proteins) induces upregulation of the junction protein claudin-5 (show CLDN5 Proteins) in endothelial cells (ECs) through activation of Jak (show JAK3 Proteins)/STAT6 and phosphorylation and translocation of FoxO1 (show FOXO1 Proteins) from the nucleus to the cytoplasm.

Cow (Bovine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. Results provide evidence that polymorphisms in STAT6 are associated with carcass and growth efficiency traits

Guinea Pig Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) interaction partners

  1. IL-4 (show IL4 Proteins) and STAT6 are related to the pathogenesis of allergic rhinitis and may be the main factors for eosinophil infiltration in allergic rhinitis.

STAT6 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with STAT6

  • signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)
  • signal transducer and activator of transcription 6 (Stat6)
  • signal transducer and activator of transcription 6-like (LOC100859543)
  • signal transducer and activator of transcription 6, interleukin-4 induced (Stat6)
  • D12S1644 protein
  • IL-4-STAT protein
  • STAT6B protein
  • STAT6C protein

Protein level used designations for STAT6

signal transducer and transcription activator 6 , STAT, interleukin4-induced , signal transducer and activator of transcription 6 , transcription factor IL-4 STAT

GENE ID SPECIES
100050053 Equus caballus
20852 Mus musculus
100859543 Gallus gallus
6778 Homo sapiens
100142679 Canis lupus familiaris
362896 Rattus norvegicus
100153518 Sus scrofa
353105 Bos taurus
100344264 Oryctolagus cuniculus
100726686 Cavia porcellus
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