Browse our Cullin 2 (CUL2) ELISA Kits

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Cullin 2 ELISA Kits (CUL2)
On are 3 Cullin 2 (CUL2) ELISA Kits from 3 different suppliers available. Additionally we are shipping Cullin 2 Antibodies (128) and Cullin 2 Proteins (5) and many more products for this protein. A total of 146 Cullin 2 products are currently listed.
1300003D18Rik, 4932411N15Rik, AI327301, ATCUL2, cul2, cullin-2, cullin 2, F22D16.2, F22D16_2, fj48a06, LOC100221330, mKIAA4106, wu:fj48a06
list all ELISA KIts Gene Name GeneID UniProt
CUL2 8453 Q13617
CUL2 71745 Q9D4H8
Rat CUL2 CUL2 361258  

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Cullin 2 (CUL2) ELISA Kits by Reactivity

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Human Cullin 2 (CUL2) interaction partners

  1. misfolded TDP-43 (show TARDBP ELISA Kits) is cleared by VHL (show VHL ELISA Kits)/CUL2 in a step-wise manner via fragmentation.

  2. Cullins are a family of NEDD8 (show NEDD8 ELISA Kits) targets important in the stabilization and degradation of proteins, such as hypoxia-inducible factor (HIF1A (show HIF1A ELISA Kits)), via Cullin-2.

  3. Nevertheless, the identification of the Cul2 box may allow prediction of Cullin specificity for all E4orf6-containing Adenoviridae.

  4. a novel link between the oncoprotein PRAME (show PRAME ELISA Kits) and the conserved EKC (show TAC4 ELISA Kits) complex

  5. Study finds that UBXN7 over-expression converts CUL2 to its neddylated form and causes the accumulation of non-ubiquitylated HIF1alpha (show HIF1A ELISA Kits).

  6. The authors applied protein-complex purification strategies and identified PRAME as a substrate recognition subunit of a Cullin2-based E3 ubiquitin ligase.

  7. The data suggest that neither HIF1alpha (show HIF1A ELISA Kits) nor CUL2 mutation may play a central role in HIF1alpha (show HIF1A ELISA Kits) activation in gastric, colorectal, breast, lung and hepatocellular carcinomas, and acute leukemias.

  8. Cullin selection is determined by specific Elongin C (show TCEB1 ELISA Kits) and Skp1 (show SKP1 ELISA Kits) sequences

  9. the HPV16 E7-associated cullin 2 ubiquitin ligase complex contributes to aberrant degradation of the pRB (show RB1 ELISA Kits) tumor suppressor in HPV16 E7-expressing cells.

  10. CUL2 is required for normal vasculogenesis, at least in part mediated by its regulation of HIF-mediated transcription.

Cow (Bovine) Cullin 2 (CUL2) interaction partners

  1. Authors show that bovine immunodeficiency virus Vif (show BTG1 ELISA Kits) interacts with Cullin 2 (CUL2), ELOB (show TCEB2 ELISA Kits)/C, and RBX1 (show RBX1 ELISA Kits), but not with CBF-beta (show CBFB ELISA Kits) or CUL5 (show CUL5 ELISA Kits), to form a CRL2 (show DAND5 ELISA Kits) E3 ubiquitin ligase and degrade the restrictive bovine APOBEC3 proteins (A3Z2Z3 and A3Z3).

Caenorhabditis elegans (C. elegans) Cullin 2 (CUL2) interaction partners

  1. CUL-2(LRR-1 (show LRR1 ELISA Kits)) and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis.

  2. CUL-2 RING E3 ubiquitin-ligase acts at multiple levels to control germline development; CUL-2 may similarly regulate germline development in other organisms as well.

  3. Results indicate that LRR-1 (show LRR1 ELISA Kits) acts as a nuclear substrate-recognition subunit of a Cullin 2-RING E3 ligase complex (CRL2 (show DAND5 ELISA Kits)(LRR-1 (show LRR1 ELISA Kits))), which ensures DNA replication integrity.

  4. The C. elegans p97/CDC-48 (show vcp ELISA Kits)-UFD-1 (show UFD1L ELISA Kits)-NPL-4 complex controls the sperm-oocyte switch by regulating CUL-2-mediated TRA-1A proteasome degradation.

  5. segregation of the germ plasm involves both stabilization of germline proteins in the germ line and cullin-dependent degradation in the soma

  6. Results establish that zyg-11 and the cullin cul-2 promote the metaphase-to-anaphase transition and M phase exit at meiosis II in Caenorhabditis elegans.

  7. Data show that inactivation of ZYG-11 produces meiotic and polarity reversal defects similar to those observed in CUL-2 mutants, suggesting that the two proteins function in the same pathways.

  8. oocyte maturation from pachytene exit and MPK-1 (show MAPK1 ELISA Kits) activation are redundantly controlled by the RBX-2-CUL-5 (show CUL5 ELISA Kits)- and RBX-1 (show RBX1 ELISA Kits)-CUL-2-based complexes.

  9. TRA-1 is regulated by degradation mediated by a CUL-2-based ubiquitin ligase complex

  10. Fem-1 protein is a substrate-specific adaptor for a CUL-2-based ubiquitin ligase.

Cullin 2 (CUL2) Antigen Profile

Antigen Summary

Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).

Alternative names and synonyms associated with Cullin 2 (CUL2)

  • Cullin-2 (cul2) Elisa Kit
  • cullin 2 (CUL2) Elisa Kit
  • cullin-2 (PTRG_05231) Elisa Kit
  • cullin-2 (cul-2) (Smp_079740) Elisa Kit
  • cullin 2 (cul2) Elisa Kit
  • cullin 2 (LOC100221330) Elisa Kit
  • cullin 2 (Cul2) Elisa Kit
  • Protein CUL-2 (cul-2) Elisa Kit
  • 1300003D18Rik Elisa Kit
  • 4932411N15Rik Elisa Kit
  • AI327301 Elisa Kit
  • ATCUL2 Elisa Kit
  • cul2 Elisa Kit
  • cullin-2 Elisa Kit
  • cullin 2 Elisa Kit
  • F22D16.2 Elisa Kit
  • F22D16_2 Elisa Kit
  • fj48a06 Elisa Kit
  • LOC100221330 Elisa Kit
  • mKIAA4106 Elisa Kit
  • wu:fj48a06 Elisa Kit

Protein level used designations for Cullin 2 (CUL2) ELISA Kits

Cullin-2 , CUL-2 , cullin-2 , cullin-2 (cul-2) , cullin 2 , cullin-2-like

100195615 Salmo salar
100174361 Pongo abelii
6343481 Pyrenophora tritici-repentis Pt-1C-BFP
8345692 Schistosoma mansoni
336088 Danio rerio
420467 Gallus gallus
450399 Pan troglodytes
698384 Macaca mulatta
100221330 Taeniopygia guttata
100395340 Callithrix jacchus
100550749 Meleagris gallopavo
8453 Homo sapiens
71745 Mus musculus
361258 Rattus norvegicus
477952 Canis lupus familiaris
535219 Bos taurus
379729 Xenopus laevis
839415 Arabidopsis thaliana
176806 Caenorhabditis elegans
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